Cell-Based Drug Delivery and Use of Nano-and Microcarriers for Cell Functionalization; Advanced Healthcare Materials; Vol. 7, iss. 3

Chi tiết về thư mục
Parent link:Advanced Healthcare Materials
Vol. 7, iss. 3.— 2018.— [P. 1–19]
Tác giả của công ty: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Tác giả khác: Timin A. S. Aleksandr Sergeevich, Litvak M. M. Maksim Mikhaylovich, Gorin D. A. Dmitry Aleksandrovich, Atochina E. N. Elena Nikolaevna, Atochin D. N. Dmitry Nikolaevich, Sukhorukov G. B. Gleb Borisovich
Tóm tắt:Title screen
Cell functionalization with recently developed various nano- and microcarriers for therapeutics has significantly expanded the application of cell therapy and targeted drug delivery for the effective treatment of a number of diseases. The aim of this progress report is to review the most recent advances in cell-based drug vehicles designed as biological transporter platforms for the targeted delivery of different drugs. For the design of cell-based drug vehicles, different pathways of cell functionalization, such as covalent and noncovalent surface modifications, internalization of carriers are considered in greater detail together with approaches for cell visualization in vivo. In addition, several animal models for the study of cell-assisted drug delivery are discussed. Finally, possible future developments and applications of cell-assisted drug vehicles toward targeted transport of drugs to a designated location with no or minimal immune response and toxicity are addressed in light of new pathways in the field of nanomedicine.
Режим доступа: по договору с организацией-держателем ресурса
Ngôn ngữ:Tiếng Anh
Được phát hành: 2018
Những chủ đề:
Truy cập trực tuyến:https://doi.org/10.1002/adhm.201700818
Định dạng: Điện tử Chương của sách
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=666994

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330 |a Cell functionalization with recently developed various nano- and microcarriers for therapeutics has significantly expanded the application of cell therapy and targeted drug delivery for the effective treatment of a number of diseases. The aim of this progress report is to review the most recent advances in cell-based drug vehicles designed as biological transporter platforms for the targeted delivery of different drugs. For the design of cell-based drug vehicles, different pathways of cell functionalization, such as covalent and noncovalent surface modifications, internalization of carriers are considered in greater detail together with approaches for cell visualization in vivo. In addition, several animal models for the study of cell-assisted drug delivery are discussed. Finally, possible future developments and applications of cell-assisted drug vehicles toward targeted transport of drugs to a designated location with no or minimal immune response and toxicity are addressed in light of new pathways in the field of nanomedicine. 
333 |a Режим доступа: по договору с организацией-держателем ресурса 
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