Trace Elements in the Lung Tissue Affected by Sarcoidosis

Bibliografiset tiedot
Parent link:Biological Trace Element Research
Vol. 196, iss. 1.— 2020.— [P. 66-73]
Yhteisötekijä: Национальный исследовательский Томский политехнический университет Инженерная школа природных ресурсов Отделение геологии
Muut tekijät: Denisova O. A. Olga Aleksandrovna, Chernogoryuk G. E. Georgiy Edinovich, Baranovskaya N. V. Nataliya Vladimirovna, Rikhvanov L. P. Leonid Petrovich, Shefer N. A. Nikolay Anatoljevich, Chernyavskaya G. M. Galina, Palchikova I. A. Inna Aleksandrovna, Kalacheva T. P. Tatjyana Petrovna
Yhteenveto:Title screen
In the lungs of 76 patients with verified sarcoidosis, 28 chemical elements were identified with neutron activation analysis. High levels of Ca, Fe, Cr, Co, Cs, Eu, Lu, Th, Hf, Au, and U and low level of Na compared to the control samples were determined in sarcoidosis. There were no significant differences in the content of Zn, Rb, La, Sm, Sr, Nd, As, Br, Ag, Tb, Sc, Ta, Sb, Ba, and Yb. Spearman correlation analysis shows multiple positive associations, with the maximum being in pairs as follows: Fe-Cr, Eu-La, Ce-Lu, Hf-Cr, Sc-Zn, Fe-Hf, Ce-Co, and Sb-Cr. These studies support the hypothesis that sarcoidosis is a response of the organism in the form of granulomatous inflammation when exposed to heavy metals and rare earth elements in the environment. We assume that the role of calcium and iron is to separate granulomas from the tissues of the body.
Режим доступа: по договору с организацией-держателем ресурса
Julkaistu: 2020
Aiheet:
Linkit:https://doi.org/10.1007/s12011-019-01915-z
Aineistotyyppi: Elektroninen Kirjan osa
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=666470
Kuvaus
Yhteenveto:Title screen
In the lungs of 76 patients with verified sarcoidosis, 28 chemical elements were identified with neutron activation analysis. High levels of Ca, Fe, Cr, Co, Cs, Eu, Lu, Th, Hf, Au, and U and low level of Na compared to the control samples were determined in sarcoidosis. There were no significant differences in the content of Zn, Rb, La, Sm, Sr, Nd, As, Br, Ag, Tb, Sc, Ta, Sb, Ba, and Yb. Spearman correlation analysis shows multiple positive associations, with the maximum being in pairs as follows: Fe-Cr, Eu-La, Ce-Lu, Hf-Cr, Sc-Zn, Fe-Hf, Ce-Co, and Sb-Cr. These studies support the hypothesis that sarcoidosis is a response of the organism in the form of granulomatous inflammation when exposed to heavy metals and rare earth elements in the environment. We assume that the role of calcium and iron is to separate granulomas from the tissues of the body.
Режим доступа: по договору с организацией-держателем ресурса
DOI:10.1007/s12011-019-01915-z