DDAO Controlled Synthesis of Organo-Modified Silica Nanoparticles with Encapsulated Fluorescent Boron Dipyrrins and Study of Their Uptake by Cancerous Cells; Molecules; Vol. 25, iss. 17

DDAO Controlled Synthesis of Organo-Modified Silica Nanoparticles with Encapsulated Fluorescent Boron Dipyrrins and Study of Their Uptake by Cancerous Cells; Molecules; Vol. 25, iss. 17

Manylion Llyfryddiaeth
Parent link:Molecules
Vol. 25, iss. 17.— 2020.— [3802, 17 p.]
Awdur Corfforaethol: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Awduron Eraill: Goncharenko A. A. Aleksandr Aleksandrovich, Tarasyuk I. A. Ilya Aleksandrovich, Marfin Yu. S., Grzhegorzhevskii K. V. Kirill Valerievich, Muslimov A. R. Albert, Bondarenko A. B. Andrey Borisovich, Lebedev M. A. Maxim Aleksandrovich, Kuzmin I. A. Ilya Alexeyevich, Vashurin A. S., Lepik K. V. Kirill Viktorovich, Timin A. S. Aleksandr Sergeevich, Rumyantsev E. V.
Crynodeb:Title screen
The design of cargo carriers with high biocompatibility, unique morphological characteristics, and capability of strong bonding of fluorescent dye is highly important for the development of a platform for smart imaging and diagnostics. In this paper, BODIPY-doped silica nanoparticles were prepared through a “one-pot” soft-template method using a sol-gel process. Several sol-gel precursors have been used in sol-gel synthesis in the presence of soft-template to obtain the silica-based materials with the most appropriate morphological features for the immobilization of BODIPY molecules. Obtained silica particles have been shown to be non-cytotoxic and can be effectively internalized into the cervical cancer cell line (HeLa). The described method of synthesis allows us to obtain silica-based carriers with an immobilized fluorescent dye that provide the possibility for real-time imaging and detection of these carriers.
Iaith:Saesneg
Cyhoeddwyd: 2020
Pynciau:
электронный ресурс
труды учёных ТПУ
silica nanoparticles
soft-template
oil-in-water
one-pot synthesis
BODIPY
Mynediad Ar-lein:https://doi.org/10.3390/molecules25173802
Fformat: Electronig Pennod Llyfr
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=664350

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