DDAO Controlled Synthesis of Organo-Modified Silica Nanoparticles with Encapsulated Fluorescent Boron Dipyrrins and Study of Their Uptake by Cancerous Cells; Molecules; Vol. 25, iss. 17
| Parent link: | Molecules Vol. 25, iss. 17.— 2020.— [3802, 17 p.] |
|---|---|
| Korporativní autor: | |
| Další autoři: | , , , , , , , , , , , |
| Shrnutí: | Title screen The design of cargo carriers with high biocompatibility, unique morphological characteristics, and capability of strong bonding of fluorescent dye is highly important for the development of a platform for smart imaging and diagnostics. In this paper, BODIPY-doped silica nanoparticles were prepared through a “one-pot” soft-template method using a sol-gel process. Several sol-gel precursors have been used in sol-gel synthesis in the presence of soft-template to obtain the silica-based materials with the most appropriate morphological features for the immobilization of BODIPY molecules. Obtained silica particles have been shown to be non-cytotoxic and can be effectively internalized into the cervical cancer cell line (HeLa). The described method of synthesis allows us to obtain silica-based carriers with an immobilized fluorescent dye that provide the possibility for real-time imaging and detection of these carriers. |
| Jazyk: | angličtina |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://doi.org/10.3390/molecules25173802 |
| Médium: | Elektronický zdroj Kapitola |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=664350 |
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| 200 | 1 | |a DDAO Controlled Synthesis of Organo-Modified Silica Nanoparticles with Encapsulated Fluorescent Boron Dipyrrins and Study of Their Uptake by Cancerous Cells |f A. A. Goncharenko, I. A. Tarasyuk, Yu. S. Marfin [et al.] | |
| 203 | |a Text |c electronic | ||
| 300 | |a Title screen | ||
| 320 | |a [References: 56 tit.] | ||
| 330 | |a The design of cargo carriers with high biocompatibility, unique morphological characteristics, and capability of strong bonding of fluorescent dye is highly important for the development of a platform for smart imaging and diagnostics. In this paper, BODIPY-doped silica nanoparticles were prepared through a “one-pot” soft-template method using a sol-gel process. Several sol-gel precursors have been used in sol-gel synthesis in the presence of soft-template to obtain the silica-based materials with the most appropriate morphological features for the immobilization of BODIPY molecules. Obtained silica particles have been shown to be non-cytotoxic and can be effectively internalized into the cervical cancer cell line (HeLa). The described method of synthesis allows us to obtain silica-based carriers with an immobilized fluorescent dye that provide the possibility for real-time imaging and detection of these carriers. | ||
| 461 | |t Molecules | ||
| 463 | |t Vol. 25, iss. 17 |v [3802, 17 p.] |d 2020 | ||
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a silica nanoparticles | |
| 610 | 1 | |a soft-template | |
| 610 | 1 | |a oil-in-water | |
| 610 | 1 | |a one-pot synthesis | |
| 610 | 1 | |a BODIPY | |
| 701 | 1 | |a Goncharenko |b A. A. |g Aleksandr Aleksandrovich | |
| 701 | 1 | |a Tarasyuk |b I. A. |g Ilya Aleksandrovich | |
| 701 | 1 | |a Marfin |b Yu. S. | |
| 701 | 1 | |a Grzhegorzhevskii |b K. V. |g Kirill Valerievich | |
| 701 | 1 | |a Muslimov |b A. R. |g Albert | |
| 701 | 1 | |a Bondarenko |b A. B. |g Andrey Borisovich | |
| 701 | 1 | |a Lebedev |b M. A. |g Maxim Aleksandrovich | |
| 701 | 1 | |a Kuzmin |b I. A. |g Ilya Alexeyevich | |
| 701 | 1 | |a Vashurin |b A. S. | |
| 701 | 1 | |a Lepik |b K. V. |g Kirill Viktorovich | |
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