Stability of a‐C:H:SiOx coating on polypropylene to chemical sterilization; Journal of Applied Polymer Science; Vol. 137, iss. 48

Stability of a‐C:H:SiOx coating on polypropylene to chemical sterilization; Journal of Applied Polymer Science; Vol. 137, iss. 48

Bibliografski detalji
Parent link:Journal of Applied Polymer Science
Vol. 137, iss. 48.— 2020.— [49570, 10 p.]
Autor kompanije: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Daljnji autori: Grenaderov A. S. Aleksandr Sergeevich, Soloviev (Solovyev) A. A. Andrey Aleksandrovich, Malashchenko V. V. Vladimir Vladimirovich, Khlusov I. A. Igor Albertovich
Sažetak:Title screen
Polypropylene (PP) is traditionally used in the production of medical devices, such as catheters, dialyzers, syringes due to its good chemical and thermal resistance, biocompatibility, and low cost. Sterilization can however damage these devices, when the polymer additive releases into physiological fluids, thereby harming the patient health. This article proposes to deposit biocompatible a?C:H:SiOx coatings onto PP surfaces and studies the coating stability after chemical sterilization. Five different chemical sterilizers, namely, hydrogen peroxide, ethanol, miramistin, formaldehyde, and ethylene oxide are used to compare their effect on the coating stability on the PP substrate. Untreated and sterilized samples are incubated in a liquid synthetic nutrient to obtain extracts that are used for sterility testing and determining the degree of interaction of samples with the nutrient medium. The changes in the coating functional groups and surface morphology are examined by using the Fourier transform infrared spectroscopy and the scanning electron microscopy, respectively. It is shown that the a?C:H:SiOx coating has a protective effect on the PP substrates subjected to chemical sterilization. The experiment results clearly showed that the ethanol sterilization causes the most serious changes in the structure of PP, and also leads to the barrier coating failure. On the other hand, ethylene oxide sterilization has a minimal effect on the structure of both uncoated and coated PP substrates.
Режим доступа: по договору с организацией-держателем ресурса
Jezik:engleski
Izdano: 2020
Teme:
электронный ресурс
труды учёных ТПУ
biomedical applications
coatings
polyolefins
биомедицинские технологии
покрытия
полиолефины
Online pristup:https://doi.org/10.1002/app.49570
Format: Elektronički Poglavlje knjige
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=663888

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