Stability of a‐C:H:SiOx coating on polypropylene to chemical sterilization; Journal of Applied Polymer Science; Vol. 137, iss. 48

Stability of a‐C:H:SiOx coating on polypropylene to chemical sterilization; Journal of Applied Polymer Science; Vol. 137, iss. 48

Detalhes bibliográficos
Parent link:Journal of Applied Polymer Science
Vol. 137, iss. 48.— 2020.— [49570, 10 p.]
Autor Corporativo: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Outros Autores: Grenaderov A. S. Aleksandr Sergeevich, Soloviev (Solovyev) A. A. Andrey Aleksandrovich, Malashchenko V. V. Vladimir Vladimirovich, Khlusov I. A. Igor Albertovich
Resumo:Title screen
Polypropylene (PP) is traditionally used in the production of medical devices, such as catheters, dialyzers, syringes due to its good chemical and thermal resistance, biocompatibility, and low cost. Sterilization can however damage these devices, when the polymer additive releases into physiological fluids, thereby harming the patient health. This article proposes to deposit biocompatible a?C:H:SiOx coatings onto PP surfaces and studies the coating stability after chemical sterilization. Five different chemical sterilizers, namely, hydrogen peroxide, ethanol, miramistin, formaldehyde, and ethylene oxide are used to compare their effect on the coating stability on the PP substrate. Untreated and sterilized samples are incubated in a liquid synthetic nutrient to obtain extracts that are used for sterility testing and determining the degree of interaction of samples with the nutrient medium. The changes in the coating functional groups and surface morphology are examined by using the Fourier transform infrared spectroscopy and the scanning electron microscopy, respectively. It is shown that the a?C:H:SiOx coating has a protective effect on the PP substrates subjected to chemical sterilization. The experiment results clearly showed that the ethanol sterilization causes the most serious changes in the structure of PP, and also leads to the barrier coating failure. On the other hand, ethylene oxide sterilization has a minimal effect on the structure of both uncoated and coated PP substrates.
Режим доступа: по договору с организацией-держателем ресурса
Idioma:inglês
Publicado em: 2020
Assuntos:
электронный ресурс
труды учёных ТПУ
biomedical applications
coatings
polyolefins
биомедицинские технологии
покрытия
полиолефины
Acesso em linha:https://doi.org/10.1002/app.49570
Formato: Recurso Electrónico Capítulo de Livro
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=663888

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