Selective antifungal activity of silver nanoparticles: A comparative study between Candida tropicalis and Saccharomyces boulardii; Colloid and Interface Science Communications; Vol. 37

Selective antifungal activity of silver nanoparticles: A comparative study between Candida tropicalis and Saccharomyces boulardii; Colloid and Interface Science Communications; Vol. 37

Bibliographische Detailangaben
Parent link:Colloid and Interface Science Communications
Vol. 37.— 2020.— [100280, 6 p.]
Körperschaft: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Weitere Verfasser: Guerra J. D. Jesus, Sandova G. Georgina, Patron A. Araceli, Avalos-Borja M., Pestryakov A. N. Aleksey Nikolaevich, Garibo D. Diana, Susarrey-Arce A. Arturo, Bogdanchikova N. Nina
Zusammenfassung:Title screen
In this study, the antifungal activity of AgNPs was tested against C. tropicalis (pathogen fungi) and S. boulardii (probiotic). The effectiveness of the AgNPs was assessed by comparing their antifungal activity with a triazole antifungal drug fluconazole and amphotericin B. The AgNPs have a polygonal-like shape (average size of 35±15 nm) with 1.2% wt. of metallic silver stabilized with 18.8% wt. of polyvinylpyrrolidone (PVP) in 80% wt. of distilled water. The results revealed that 35 [mu]g/mL of fluconazole inhibits 55-60% of both fungal cell growth. As for amphotericin B, 5 [mu]g/mL is sufficient to inhibit more than 95% of both fungal cells. For AgNPs, 25 [mu]g/mL was needed to inhibit 90% of the C. tropicalis cell growth, but remarkably, 50% of the S. boulardii cell population remains viable, which can potentiate cell reproduction. Our results could initiate the development of AgNPs possessing selective specificity against pathogenic fungal species.
Режим доступа: по договору с организацией-держателем ресурса
Sprache:Englisch
Veröffentlicht: 2020
Schlagworte:
электронный ресурс
труды учёных ТПУ
silver nanoparticles
antifungal
probiotic
pathogenic
yeast
наночастицы
серебро
пробиотики
Online-Zugang:https://doi.org/10.1016/j.colcom.2020.100280
Format: Elektronisch Buchkapitel
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=663827

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