Selective antifungal activity of silver nanoparticles: A comparative study between Candida tropicalis and Saccharomyces boulardii; Colloid and Interface Science Communications; Vol. 37
| Parent link: | Colloid and Interface Science Communications Vol. 37.— 2020.— [100280, 6 p.] |
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| مؤلف مشترك: | |
| مؤلفون آخرون: | , , , , , , , |
| الملخص: | Title screen In this study, the antifungal activity of AgNPs was tested against C. tropicalis (pathogen fungi) and S. boulardii (probiotic). The effectiveness of the AgNPs was assessed by comparing their antifungal activity with a triazole antifungal drug fluconazole and amphotericin B. The AgNPs have a polygonal-like shape (average size of 35±15 nm) with 1.2% wt. of metallic silver stabilized with 18.8% wt. of polyvinylpyrrolidone (PVP) in 80% wt. of distilled water. The results revealed that 35 [mu]g/mL of fluconazole inhibits 55-60% of both fungal cell growth. As for amphotericin B, 5 [mu]g/mL is sufficient to inhibit more than 95% of both fungal cells. For AgNPs, 25 [mu]g/mL was needed to inhibit 90% of the C. tropicalis cell growth, but remarkably, 50% of the S. boulardii cell population remains viable, which can potentiate cell reproduction. Our results could initiate the development of AgNPs possessing selective specificity against pathogenic fungal species. Режим доступа: по договору с организацией-держателем ресурса |
| اللغة: | الإنجليزية |
| منشور في: |
2020
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1016/j.colcom.2020.100280 |
| التنسيق: | الكتروني فصل الكتاب |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=663827 |
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| 200 | 1 | |a Selective antifungal activity of silver nanoparticles: A comparative study between Candida tropicalis and Saccharomyces boulardii |f J. D. Guerra, G. Sandova, A. Patron [et al.] | |
| 203 | |a Text |c electronic | ||
| 300 | |a Title screen | ||
| 320 | |a [References: 43 tit.] | ||
| 330 | |a In this study, the antifungal activity of AgNPs was tested against C. tropicalis (pathogen fungi) and S. boulardii (probiotic). The effectiveness of the AgNPs was assessed by comparing their antifungal activity with a triazole antifungal drug fluconazole and amphotericin B. The AgNPs have a polygonal-like shape (average size of 35±15 nm) with 1.2% wt. of metallic silver stabilized with 18.8% wt. of polyvinylpyrrolidone (PVP) in 80% wt. of distilled water. The results revealed that 35 [mu]g/mL of fluconazole inhibits 55-60% of both fungal cell growth. As for amphotericin B, 5 [mu]g/mL is sufficient to inhibit more than 95% of both fungal cells. For AgNPs, 25 [mu]g/mL was needed to inhibit 90% of the C. tropicalis cell growth, but remarkably, 50% of the S. boulardii cell population remains viable, which can potentiate cell reproduction. Our results could initiate the development of AgNPs possessing selective specificity against pathogenic fungal species. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
| 461 | |t Colloid and Interface Science Communications | ||
| 463 | |t Vol. 37 |v [100280, 6 p.] |d 2020 | ||
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a silver nanoparticles | |
| 610 | 1 | |a antifungal | |
| 610 | 1 | |a probiotic | |
| 610 | 1 | |a pathogenic | |
| 610 | 1 | |a yeast | |
| 610 | 1 | |a наночастицы | |
| 610 | 1 | |a серебро | |
| 610 | 1 | |a пробиотики | |
| 701 | 1 | |a Guerra |b J. D. |g Jesus | |
| 701 | 1 | |a Sandova |b G. |g Georgina | |
| 701 | 1 | |a Patron |b A. |g Araceli | |
| 701 | 1 | |a Avalos-Borja |b M. | |
| 701 | 1 | |a Pestryakov |b A. N. |c Chemist |c Professor of Tomsk Polytechnic University, Doctor of Chemical Science |f 1963- |g Aleksey Nikolaevich |3 (RuTPU)RU\TPU\pers\30471 |9 14796 | |
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