The Mitochondrial Permeability Transition Pore – a Regulator of the Resistance of the Heart to Reperfusion; Neuroscience and Behavioral Physiology; Vol. 48, iss. 8

The Mitochondrial Permeability Transition Pore – a Regulator of the Resistance of the Heart to Reperfusion; Neuroscience and Behavioral Physiology; Vol. 48, iss. 8

Bibliographic Details
Parent link:Neuroscience and Behavioral Physiology.— , 1967-
Vol. 48, iss. 8.— 2019.— [P. 943–953]
Corporate Author: Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Лаборатория № 31 ядерного реактора (Лаборатория № 31 ЯР)
Other Authors: Naryzhnaya N. V. Nataliya Vladimirovna, Maslov L. N. Leonid Nikolaevich, Lishmanov Yu. B. Yury Borisovich, Nesterov E. A. Evgeny Alexandrovich, Jaggi A. S. Amteshwar Singh, Suleiman S. Saadeh
Summary:Title screen
The most important event in the formation of reperfusion injury to the heart has been shown to be the opening of mitochondrial permeability transition pores (mPTP). mPTP opening is followed by activation of apoptosis, necroptosis, and cardiomyocyte death. Experimental studies have shown that inhibition of mPTP opening decreases infarct size and that conditioning actions on the myocardium are mediated via decreases in the sensitivity of mPTP to opening factors. The present article reviews existing data on the structure and regulation of mPTP in conditions of reperfusion injury to the heart.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2019
Subjects:
электронный ресурс
труды учёных ТПУ
myocardium
reperfusion
MPT pores
mitochondria
миокард
реперфузия
митохондрии
Online Access:https://doi.org/10.1007/s11055-019-00823-y
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=663726

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