99mTc-labeled nanocolloid drugs: development methods

Bibliographic Details
Parent link:Scientific Reports
Vol. 10, iss. 1.— 2020.— [14013, 9 p.]
Corporate Author: Национальный исследовательский Томский политехнический университет Физико-технический институт Лаборатория радиационного контроля № 31
Other Authors: Sadkin V. L. Vladimir Leonidovich, Skuridin V. S. Viktor Sergeyevich, Nesterov E. A. Evgeny Alexandrovich, Stasyuk (Stasiuk) E. S. Elena Sergeyevna, Rogov A. S. Alexander Sergeyevich, Varlamova N. V. Natalya Valeryevna, Zelchan R. V. Roman Vladimirovich
Summary:Title screen
The work considers the problem of obtaining nanocolloid radiopharmaceuticals (RPs) and studying their functional suitability for diagnosing sentinel lymph nodes (SLN) in cancer patients. Two principal approaches to the formation of technetium-99m-labeled particles based on inorganic and organic matrices were considered when carrying out research to develop methods for the production of nanocolloid RPs. The composition of the reagents and the conditions for obtaining nanocolloid radiopharmaceuticals were determined. The functional suitability of new RPs for scintigraphic diagnostics of sentinel lymph nodes has been studied.
Language:English
Published: 2020
Subjects:
Online Access:https://doi.org/10.1038/s41598-020-70991-2
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=663262

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200 1 |a 99mTc-labeled nanocolloid drugs: development methods  |f V. L. Sadkin, V. S. Skuridin, E. A. Nesterov [et al.] 
203 |a Text  |c electronic 
300 |a Title screen 
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330 |a The work considers the problem of obtaining nanocolloid radiopharmaceuticals (RPs) and studying their functional suitability for diagnosing sentinel lymph nodes (SLN) in cancer patients. Two principal approaches to the formation of technetium-99m-labeled particles based on inorganic and organic matrices were considered when carrying out research to develop methods for the production of nanocolloid RPs. The composition of the reagents and the conditions for obtaining nanocolloid radiopharmaceuticals were determined. The functional suitability of new RPs for scintigraphic diagnostics of sentinel lymph nodes has been studied. 
461 |t Scientific Reports 
463 |t Vol. 10, iss. 1  |v [14013, 9 p.]  |d 2020 
610 1 |a электронный ресурс 
610 1 |a труды учёных ТПУ 
610 1 |a cancer imaging 
610 1 |a nanoparticle synthesis 
610 1 |a drug development 
610 1 |a рак 
610 1 |a лекарства 
701 1 |a Sadkin  |b V. L.  |c Physicist  |c Associate Scientist of Tomsk Polytechnic University, candidate of technical Sciences  |f 1986-  |g Vladimir Leonidovich  |3 (RuTPU)RU\TPU\pers\32654  |9 16553 
701 1 |a Skuridin  |b V. S.  |c Physicist, Specialist in the field of nuclear power engineering  |c Professor of Tomsk Polytechnic University, Doctor of technical sciences  |f 1946-  |g Viktor Sergeyevich  |3 (RuTPU)RU\TPU\pers\32655  |9 16554 
701 1 |a Nesterov  |b E. A.  |c Physicist, Specialist in the field of nuclear power engineering  |c Researcher of Tomsk Polytechnic University  |f 1976-  |g Evgeny Alexandrovich  |3 (RuTPU)RU\TPU\pers\32657  |9 16556 
701 1 |a Stasyuk (Stasiuk)  |b E. S.  |c Specialist in the field of nuclear power engineering  |c Researcher of Tomsk Polytechnic University, Candidate of technical sciences  |f 1978-  |g Elena Sergeyevna  |3 (RuTPU)RU\TPU\pers\32656  |9 16555 
701 1 |a Rogov  |b A. S.  |c Radiochemist  |c Engineer of Tomsk Polytechnic University  |f 1986-  |g Alexander Sergeyevich  |3 (RuTPU)RU\TPU\pers\32658  |9 16557 
701 1 |a Varlamova  |b N. V.  |c biochemist  |c Researcher of Tomsk Polytechnic University, Candidate of biological sciences  |f 1975-  |g Natalya Valeryevna  |3 (RuTPU)RU\TPU\pers\32659 
701 1 |a Zelchan  |b R. V.  |c specialist in the field of medical technology  |c laboratory Tomsk Polytechnic University  |f 1984-  |g Roman Vladimirovich  |3 (RuTPU)RU\TPU\pers\34194 
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