Development of a bone substitute material based on additive manufactured Ti6Al4V alloys modified with bioceramic calcium carbonate coating: Characterization and antimicrobial properties; Ceramics International; Vol. 46, iss. 16, Pt. A
| Parent link: | Ceramics International Vol. 46, iss. 16, Pt. A.— 2020.— [P. 25661-25670] |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , , , , , , , , , , , |
| Sumario: | Title screen This investigation shows that composite structures based on additive manufactured electron beam melted Ti6Al4V scaffolds coated with calcium carbonate particles can be used as a potential biocomposites for bone substitutes. A continuous bioceramic coating of CaCO3 was deposited on additive manufactured titanium alloy under the influence of ultrasound. XRD analysis revealed the formation of a mixture of calcite and vaterite phases. CaCO3 coating led to decreasing roughness of additively manufactured (AM) scaffolds and improved surface hydrophilicity. In vitro assay demonstrated enhanced inorganic bone phase formation on the surface of CaCO3-coated AM scaffolds compared to as-manufactured ones. The short-term adhesion of S. aureus onto sample surface was evaluated by fluorescent microscopy 0, 3, and 72 h after cell seeding. It revealed that the surface modification resulted in the decreased number of bacteria attached to the surface after CaCO3 deposition. The morphology, roughness, solubility and superhydrophilic character of the CaCO3 coated EBM-manufactured Ti6Al4V alloy surface are suggested as factors contributing to preventing S. aureus adhesion. Thus, the developed biocomposites based on additively manufactured Ti6Al4V alloy scaffolds and CaCO3 coating can be successfully used in bone tissue regeneration providing the effective growth of inorganic bone phase and preventing the bacteria adhesion. Режим доступа: по договору с организацией-держателем ресурса |
| Lenguaje: | inglés |
| Publicado: |
2020
|
| Materias: | |
| Acceso en línea: | https://doi.org/10.1016/j.ceramint.2020.07.041 |
| Formato: | Electrónico Capítulo de libro |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=663182 |
MARC
| LEADER | 00000naa0a2200000 4500 | ||
|---|---|---|---|
| 001 | 663182 | ||
| 005 | 20250424160457.0 | ||
| 035 | |a (RuTPU)RU\TPU\network\34351 | ||
| 090 | |a 663182 | ||
| 100 | |a 20210128d2020 k||y0rusy50 ba | ||
| 101 | 0 | |a eng | |
| 135 | |a drcn ---uucaa | ||
| 181 | 0 | |a i | |
| 182 | 0 | |a b | |
| 200 | 1 | |a Development of a bone substitute material based on additive manufactured Ti6Al4V alloys modified with bioceramic calcium carbonate coating: Characterization and antimicrobial properties |f M. A. Surmeneva, E. A. Chudinova, R. V. Chernozem [et al.] | |
| 203 | |a Text |c electronic | ||
| 300 | |a Title screen | ||
| 320 | |a [References: 59 tit.] | ||
| 330 | |a This investigation shows that composite structures based on additive manufactured electron beam melted Ti6Al4V scaffolds coated with calcium carbonate particles can be used as a potential biocomposites for bone substitutes. A continuous bioceramic coating of CaCO3 was deposited on additive manufactured titanium alloy under the influence of ultrasound. XRD analysis revealed the formation of a mixture of calcite and vaterite phases. CaCO3 coating led to decreasing roughness of additively manufactured (AM) scaffolds and improved surface hydrophilicity. In vitro assay demonstrated enhanced inorganic bone phase formation on the surface of CaCO3-coated AM scaffolds compared to as-manufactured ones. The short-term adhesion of S. aureus onto sample surface was evaluated by fluorescent microscopy 0, 3, and 72 h after cell seeding. It revealed that the surface modification resulted in the decreased number of bacteria attached to the surface after CaCO3 deposition. The morphology, roughness, solubility and superhydrophilic character of the CaCO3 coated EBM-manufactured Ti6Al4V alloy surface are suggested as factors contributing to preventing S. aureus adhesion. Thus, the developed biocomposites based on additively manufactured Ti6Al4V alloy scaffolds and CaCO3 coating can be successfully used in bone tissue regeneration providing the effective growth of inorganic bone phase and preventing the bacteria adhesion. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
| 461 | |t Ceramics International | ||
| 463 | |t Vol. 46, iss. 16, Pt. A |v [P. 25661-25670] |d 2020 | ||
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a bioceramic coating | |
| 610 | 1 | |a electron beam melting | |
| 610 | 1 | |a calcium carbonate | |
| 610 | 1 | |a ultrasound | |
| 610 | 1 | |a simulated body fluid | |
| 610 | 1 | |a staphylococcus aureus | |
| 610 | 1 | |a биокерамические материалы | |
| 610 | 1 | |a электронно-лучевая плавка | |
| 610 | 1 | |a карбонат кальция | |
| 610 | 1 | |a ультразвуковые исследования | |
| 610 | 1 | |a стафилококки | |
| 701 | 1 | |a Surmeneva |b M. A. |c specialist in the field of material science |c engineer-researcher of Tomsk Polytechnic University, Associate Scientist |f 1984- |g Maria Alexandrovna |3 (RuTPU)RU\TPU\pers\31894 |9 15966 | |
| 701 | 1 | |a Chudinova |b E. A. |c physicist |c laboratory assistant of Tomsk Polytechnic University |f 1993- |g Ekaterina Aleksandrovna |3 (RuTPU)RU\TPU\pers\34765 |9 18115 | |
| 701 | 1 | |a Chernozem |b R. V. |c physicist |c Associate Professor of Tomsk Polytechnic University |f 1992- |g Roman Viktorovich |3 (RuTPU)RU\TPU\pers\36450 |9 19499 | |
| 701 | 1 | |a Lapanje |b A. |g Ales | |
| 701 | 1 | |a Koptyug |b A. V. |g Andrey Valentinovich | |
| 701 | 1 | |a Rijavec |b T. |g Tomaz | |
| 701 | 1 | |a Loza |b K. |g Kateryna | |
| 701 | 1 | |a Prymak |b O. |g Oleg | |
| 701 | 1 | |a Epple |b M. |g Matthias | |
| 701 | 1 | |a Wittmar |b A. |g Alexandra | |
| 701 | 1 | |a Ulbricht |b M. |g Mathias | |
| 701 | 1 | |a Surmenev |b R. A. |c physicist |c Associate Professor of Tomsk Polytechnic University, Senior researcher, Candidate of physical and mathematical sciences |f 1982- |g Roman Anatolievich |3 (RuTPU)RU\TPU\pers\31885 |9 15957 | |
| 712 | 0 | 2 | |a Национальный исследовательский Томский политехнический университет |b Исследовательская школа физики высокоэнергетических процессов |c (2017- ) |3 (RuTPU)RU\TPU\col\23551 |
| 801 | 2 | |a RU |b 63413507 |c 20210128 |g RCR | |
| 850 | |a 63413507 | ||
| 856 | 4 | |u https://doi.org/10.1016/j.ceramint.2020.07.041 | |
| 942 | |c CF | ||