Time-stable wetting effect of plasma-treated biodegradable scaffolds functionalized with graphene oxide

書目詳細資料
Parent link:Surface and Coatings Technology
Vol. 388.— 2020.— [125560, 8 p.]
Corporate Authors: Национальный исследовательский Томский политехнический университет Инженерная школа ядерных технологий Научно-образовательный центр Б. П. Вейнберга, Национальный исследовательский Томский политехнический университет Исследовательская школа физики высокоэнергетических процессов, Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
其他作者: Lipovka A. A. Anna Anatolyevna, Rodriguez (Rodriges) Contreras R. D. Raul David, Bolbasov E. N. Evgeny Nikolaevich, Marjin (Maryin) P. V. Pavel Vladimirovich, Tverdokhlebov S. I. Sergei Ivanovich, Sheremet E. S. Evgeniya Sergeevna
總結:Title screen
The polymer scaffolds surfaces are inherently hydrophobic what limits its performance as implants and compatibility with human tissue essential for such applications as tissue engineering, nerve regeneration, drug delivery, etc. The plasma treatment was demonstrated to change the wetting properties of scaffolds making them hydrophilic. However, that is not a lasting effect. In this work, we aim at addressing this problem with systematic time-stability investigation of scaffolds functionalized with graphene oxide (GO) layers. To this end, we used several polymers including polycaprolactone (PCL), poly-L-lactic acid (PLLA), l-lactide-co-glycolide copolymer (PLGA) and l-lactide-co-caprolactone copolymer (PLC) functionalized with GO, evaluating also control samples without any treatment and treated by plasma. Our results demonstrate that the GO coating provides a successful and stable hydrophilic functionality to all polymer scaffolds here investigated. Contrary to plasma treatment used as a reference for the surface-wettability provider, only the GO effects remain stable for extended periods of up to 30 days. This work contributes to the robust application of graphene-functionalized polymer scaffolds with long lifetime hydrophilicity.
Режим доступа: по договору с организацией-держателем ресурса
語言:英语
出版: 2020
主題:
在線閱讀:https://doi.org/10.1016/j.surfcoat.2020.125560
格式: 電子 Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=662147

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