Feasibility of clinical electron beam formation using polymer materials produced by fused deposition modeling; Physica Medica; Vol. 64

Bibliografiset tiedot
Parent link:Physica Medica
Vol. 64.— 2019.— [P. 188-194]
Yhteisötekijät: Национальный исследовательский Томский политехнический университет Инженерная школа ядерных технологий Отделение ядерно-топливного цикла, Национальный исследовательский Томский политехнический университет Исследовательская школа физики высокоэнергетических процессов
Muut tekijät: Miloichikova I. A. Irina Alekseevna, Bulavskaya A. A. Angelina Aleksandrovna, Cherepennikov Yu. M. Yuriy Mihaylovich, Gavrikov B. M. Boris Mikhaylovich, Gargioni E. Elisabetta, Belousov D. A. Dmitry Aleksandrovich, Stuchebrov S. G. Sergey Gennadevich
Yhteenveto:Title screen
The main challenge in electron external beam radiation therapy with clinical accelerators is the absence of integrated systems to form irregular fields. The current approach to provide conformal irradiation is to use additional metallic shaping blocks, with inefficient and expensive workflows. This work presents a simple method to form therapeutic electron fields using 3D printed samples. These samples are manufactured by fused deposition modeling, which can affect crucial properties, such as material homogeneity, due to the presence of residual air-filled cavities. The applicability of this method was therefore investigated with a set of experiments and Monte Carlo simulations aimed at determining the electron depth dose distribution in polymer materials. The results show that therapeutic electron beams with energies 6–20?MeV can be effectively absorbed using these polymeric samples. The model developed in this study provides a way to assess the dose distribution in such materials and to calculate the appropriate thickness of polymer samples for therapeutic electron beam formation. It is shown that for total absorption of 6?MeV electron beams the material thickness should be at least 4?cm, while this value should be at least 8?cm for 12?MeV and 11?cm for 20?MeV, respectively. The results can be used to further develop 3D printing procedures for medical electron beam profile formation, allowing the creation of a collimator or absorber with patient-specific configuration using rapid prototyping systems, thus contributing to improve the accuracy of dose delivery in electron radiotherapy within a short manufacturing time.
Режим доступа: по договору с организацией-держателем ресурса
Kieli:englanti
Julkaistu: 2019
Aiheet:
Linkit:https://doi.org/10.1016/j.ejmp.2019.07.014
Aineistotyyppi: Elektroninen Kirjan osa
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=661834

MARC

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200 1 |a Feasibility of clinical electron beam formation using polymer materials produced by fused deposition modeling  |f I. A. Miloichikova, A. A. Bulavskaya, Yu. M. Cherepennikov [et al.] 
203 |a Text  |c electronic 
300 |a Title screen 
320 |a [References: 62 tit.] 
330 |a The main challenge in electron external beam radiation therapy with clinical accelerators is the absence of integrated systems to form irregular fields. The current approach to provide conformal irradiation is to use additional metallic shaping blocks, with inefficient and expensive workflows. This work presents a simple method to form therapeutic electron fields using 3D printed samples. These samples are manufactured by fused deposition modeling, which can affect crucial properties, such as material homogeneity, due to the presence of residual air-filled cavities. The applicability of this method was therefore investigated with a set of experiments and Monte Carlo simulations aimed at determining the electron depth dose distribution in polymer materials. The results show that therapeutic electron beams with energies 6–20?MeV can be effectively absorbed using these polymeric samples. The model developed in this study provides a way to assess the dose distribution in such materials and to calculate the appropriate thickness of polymer samples for therapeutic electron beam formation. It is shown that for total absorption of 6?MeV electron beams the material thickness should be at least 4?cm, while this value should be at least 8?cm for 12?MeV and 11?cm for 20?MeV, respectively. The results can be used to further develop 3D printing procedures for medical electron beam profile formation, allowing the creation of a collimator or absorber with patient-specific configuration using rapid prototyping systems, thus contributing to improve the accuracy of dose delivery in electron radiotherapy within a short manufacturing time. 
333 |a Режим доступа: по договору с организацией-держателем ресурса 
461 |t Physica Medica 
463 |t Vol. 64  |v [P. 188-194]  |d 2019 
610 1 |a электронный ресурс 
610 1 |a труды учёных ТПУ 
610 1 |a electron beam 
610 1 |a fused deposition modeling 
610 1 |a radiation therapy 
610 1 |a ABS and HIPS plastics 
610 1 |a электронные лучи 
610 1 |a моделирование 
610 1 |a отложения 
610 1 |a радиационная терапия 
610 1 |a пластмассы 
701 1 |a Miloichikova  |b I. A.  |c physicist  |c Associate Professor of Tomsk Polytechnic University, Candidate of Physical and Mathematical Sciences  |f 1988-  |g Irina Alekseevna  |3 (RuTPU)RU\TPU\pers\35525  |9 18707 
701 1 |a Bulavskaya  |b A. A.  |c Specialist in the field of nuclear technologies  |c Senior Lecturer of Tomsk Polytechnic University, Candidate of Physical and Mathematical Sciences  |f 1993-  |g Angelina Aleksandrovna  |3 (RuTPU)RU\TPU\pers\45898  |9 22019 
701 1 |a Cherepennikov  |b Yu. M.  |c physicist  |c Associate Professor of Tomsk Polytechnic University, Candidate of Sciences  |f 1989-  |g Yuriy Mihaylovich  |3 (RuTPU)RU\TPU\pers\31561  |9 15721 
701 1 |a Gavrikov  |b B. M.  |g Boris Mikhaylovich 
701 1 |a Gargioni  |b E.  |g Elisabetta 
701 1 |a Belousov  |b D. A.  |g Dmitry Aleksandrovich 
701 1 |a Stuchebrov  |b S. G.  |c physicist  |c Associate Professor of Tomsk Polytechnic University, Candidate of Physical and Mathematical Sciences  |f 1981-  |g Sergey Gennadevich  |3 (RuTPU)RU\TPU\pers\31559  |9 15719 
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