Antibacterial potential of Zn- and Cu-substituted hydroxyapatite-based coatings deposited by RF-magnetron sputtering

Antibacterial potential of Zn- and Cu-substituted hydroxyapatite-based coatings deposited by RF-magnetron sputtering

Bibliographic Details
Parent link:	Journal of Physics: Conference Series Vol. 1393 : Gas Discharge Plasmas and Their Applications (GDP 2019).— 2019.— [012118, 8 p.]
Corporate Author:	Национальный исследовательский Томский политехнический университет Инженерная школа новых производственных технологий Научно-производственная лаборатория "Импульсно-пучковых, электроразрядных и плазменных технологий"
Other Authors:	Prosolov K. A. Konstantin Aleksandrovich, Belyavskaya O. A. Olga Andreevna, Bolat-ool A. A. Anna Andriyanovna, Khlusov I. A. Igor Albertovich, Nikolaeva O. O. Olga Olegovna, Prosolov A. B. Aleksandr Borisovich, Mitrichenko D. V. Dmitry Vladimirovich, Komkov A. R. Andry Rashitovich, Sharkeev Yu. P. Yury Petrovich
Summary:	Title screen The market of medical devices demanding new products for treatment of bone fractures. The demand is growing due to aging population and increased physical activity in senior people. We introduce newly developed implants - intramedullary fixators made from a set of biocompatible alloys including commercially pure titanium, Ti-6Al-7Nb and magnesium-based alloy. Surface of these implants is modified by Zn- or Cu-substituted hydroxyapatites coatings deposited by RF magnetron sputtering in order to diminish the risk of post-operative infection. The amorphous layers were deposited on the surface of biocompatible substrates for all deposition runs. Post-deposition annealing in air at the temperature of 700°C allowed us to crystallize coating in a way that the main hydroxyapatite peaks are well defined and lattice parameters calculated proving Zn2+ and Cu2+ substitution. The bacteriostatic effect of the coatings against the pathogenic strain 209P of Staphylococcus aureus was shown in vitro independent on the material of the metallic substrate
Published:	2019
Subjects:	электронный ресурс труды учёных ТПУ антибактериальные свойства гидроксиапатиты ВЧ-магнетронное распыление
Online Access:	https://doi.org/10.1088/1742-6596/1393/1/012118
Format:	Electronic Book Chapter
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=661677

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