Polylactic Acid Properties after Steam Sterilization and Possibility of Its Using as a Corneal Implant; AIP Conference Proceedings; Vol. 2167 : Advanced Materials with Hierarchical Structure for New Technologies and Reliable Structures 2019 (AMHS'19)

Bibliographic Details
Parent link:AIP Conference Proceedings
Vol. 2167 : Advanced Materials with Hierarchical Structure for New Technologies and Reliable Structures 2019 (AMHS'19).— 2019.— [020104, 4 p.]
Main Author: Filippova E. O. Ekaterina Olegovna
Corporate Authors: Национальный исследовательский Томский политехнический университет Инженерная школа ядерных технологий Лаборатория плазменных гибридных систем, Национальный исследовательский Томский политехнический университет Исследовательская школа физики высокоэнергетических процессов
Other Authors: Ivanova N. M. Nina Mikhailovna
Summary:Title screen
The purpose of this research is the study of the influence of thin polylactic acid (PLA) films implantation on the corneal morphology in vivo experiment. Studies were performed on 8 pubescent female Sylvilagus bachmani rabbits. PLA films were implanted into the anterior chamber of one animal eye. The feedstock for the films was obtained by dissolving PLA in the chloroform. Before the implantation PLA films were sterilized. The overall duration of the in vivo experiment comprised 21 days. Such methods as visual check, photographic registration, non-contact ocular tonometry and optical coherent tomography of cornea were also used in course of the experiment. Sampling was performed on day 21 after the start of the experiment for morphology studying. Results showed that the implantation of the PLA films into the anterior chamber of eye does not induce an inflammatory reaction and does not increase an intraocular pressure. The study showed the possibility of PLA films using as a corneal implant.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2019
Subjects:
Online Access:https://doi.org/10.1063/1.5131971
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=661487

MARC

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330 |a The purpose of this research is the study of the influence of thin polylactic acid (PLA) films implantation on the corneal morphology in vivo experiment. Studies were performed on 8 pubescent female Sylvilagus bachmani rabbits. PLA films were implanted into the anterior chamber of one animal eye. The feedstock for the films was obtained by dissolving PLA in the chloroform. Before the implantation PLA films were sterilized. The overall duration of the in vivo experiment comprised 21 days. Such methods as visual check, photographic registration, non-contact ocular tonometry and optical coherent tomography of cornea were also used in course of the experiment. Sampling was performed on day 21 after the start of the experiment for morphology studying. Results showed that the implantation of the PLA films into the anterior chamber of eye does not induce an inflammatory reaction and does not increase an intraocular pressure. The study showed the possibility of PLA films using as a corneal implant. 
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