In Vitro Activity Assays of Sputtered HAp Coatings with SiC Addition in Various Simulated Biological Fluids; Coatings; Vol. 9, iss. 6

Manylion Llyfryddiaeth
Parent link:Coatings
Vol. 9, iss. 6.— 2019.— [389, 17 p.]
Awdur Corfforaethol: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий Научно-исследовательский центр "Физическое материаловедение и композитные материалы"
Awduron Eraill: Vladesku A. Alina, Parau A. C. Anca Constantina, Pana I. Iulian, Kotrut M. K. Mikhay Kosmin, Constantin L. R. Lidia, Braic V. T. Viorel, Vranceanu D. M. Diana Maria
Crynodeb:Title screen
Considering the requirements of medical implantable devices, it is pointed out that biomaterials should play a more sophisticated, longer-term role in the customization and optimization of the material–tissue interface in order to ensure the best long-term clinical outcomes. The aim of this contribution was to assess the performance of silicon carbide–hydroxyapatite in various simulated biological fluids (Dulbecco’s modified Eagle’s medium (DMEM), simulated body fluid (SBF), and phosphate buffer solution (PBS)) through immersion assays for 21 days at 37 ± 0.5 °C and to evaluate the electrochemical behavior. The coatings were prepared on Ti6Al4V alloy substrates by magnetron sputtering method using two cathodes made of hydroxyapatite and silicon carbide (SiC). After immersion assays the coating’s surface was analyzed in terms of morphology, chemical and phase composition, and chemical bonds. According to the electrochemical behavior in the media investigated at 37 ± 0.5 °C, SiC addition inhibits the dissolution of the hydroxyapatite in DMEM acellular media. Furthermore, after adding SiC, the slow degradation of hydroxyapatite in PBS and SBF media as well as biomineralization in DMEM were observed.
Iaith:Saesneg
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://doi.org/10.3390/coatings9060389
Fformat: xMaterials Electronig Pennod Llyfr
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=661446

MARC

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200 1 |a In Vitro Activity Assays of Sputtered HAp Coatings with SiC Addition in Various Simulated Biological Fluids  |f A. Vladesku, A. C. Parau, I. Pana [et al.] 
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330 |a Considering the requirements of medical implantable devices, it is pointed out that biomaterials should play a more sophisticated, longer-term role in the customization and optimization of the material–tissue interface in order to ensure the best long-term clinical outcomes. The aim of this contribution was to assess the performance of silicon carbide–hydroxyapatite in various simulated biological fluids (Dulbecco’s modified Eagle’s medium (DMEM), simulated body fluid (SBF), and phosphate buffer solution (PBS)) through immersion assays for 21 days at 37 ± 0.5 °C and to evaluate the electrochemical behavior. The coatings were prepared on Ti6Al4V alloy substrates by magnetron sputtering method using two cathodes made of hydroxyapatite and silicon carbide (SiC). After immersion assays the coating’s surface was analyzed in terms of morphology, chemical and phase composition, and chemical bonds. According to the electrochemical behavior in the media investigated at 37 ± 0.5 °C, SiC addition inhibits the dissolution of the hydroxyapatite in DMEM acellular media. Furthermore, after adding SiC, the slow degradation of hydroxyapatite in PBS and SBF media as well as biomineralization in DMEM were observed. 
461 |t Coatings 
463 |t Vol. 9, iss. 6  |v [389, 17 p.]  |d 2019 
610 1 |a электронный ресурс 
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610 1 |a SBF 
610 1 |a DMEM 
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610 1 |a hydroxyapatite 
610 1 |a silicon 
610 1 |a magnetron sputtering 
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701 1 |a Parau  |b A. C.  |g Anca Constantina 
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701 1 |a Kotrut  |b M. K.  |c physicist  |c physicist Professor Tomsk Polytechnic University, Ph.D.  |f 1977-  |g Mikhay Kosmin  |3 (RuTPU)RU\TPU\pers\37467 
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