Polyelectrolyte multilayer microchamber-arrays for in-situ cargo release: Low frequency vs. medical frequency range ultrasound; Colloids and Surfaces A: Physicochemical and Engineering Aspects; Vol. 547

Polyelectrolyte multilayer microchamber-arrays for in-situ cargo release: Low frequency vs. medical frequency range ultrasound; Colloids and Surfaces A: Physicochemical and Engineering Aspects; Vol. 547

Détails bibliographiques
Parent link:	Colloids and Surfaces A: Physicochemical and Engineering Aspects Vol. 547.— 2018.— [P. 19-27]
Collectivité auteur:	Национальный исследовательский Томский политехнический университет Инженерная школа ядерных технологий Научно-образовательный центр Б. П. Вейнберга
Autres auteurs:	Li Wenhao, Gay Meyu, Frue Yo. K. Yokhannes Kristof, Kudryavtseva V. L. Valeriya Lvovna, Sukhorukov G. B. Gleb Borisovich
Résumé:	Title screen An implantable ultrasound triggered controlled release micro-chamber (MC) array based on polylactic acid (PLA) sealed polyelectrolyte multilayers (PEM) is presented. In this work Rhodamine B (RhB) nano-precipitates are loaded as model cargo and sealed water tight within micro-air bubbles. Cargo release at low frequency (LFUS (37 kHz)) and high frequency ultrasound (HFUS (2 MHz, medical range)) is compared. The release speed and mechanism varies significantly between both ultrasound frequencies, allowing for a 60 times faster MC opening at HFUS. LFUS MC opening is based on material fatigue combined with thermo-acoustic effects while strong thermo-acoustic effects are responsible for MC opening at HFUS. The slower MC opening at LFUS allows for controlling the release amount and enables multiple release pulses compared to HFUS. Not PLA coated and no air bubble entrapping PEM thin films are in case of HFUS destroyed, while no interaction is determined at LFUS. Режим доступа: по договору с организацией-держателем ресурса
Langue:	anglais
Publié:	2018
Sujets:	электронный ресурс труды учёных ТПУ polyelectrolyte multilayers biopolymer encapsulation controlled releaselow frequency ultrasound medical frequency ultrasound полиэлектролиты биополимеры инкапсуляция ультразвук частота
Accès en ligne:	https://doi.org/10.1016/j.colsurfa.2018.03.031
Format:	Électronique Chapitre de livre
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=661178

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