Janus glycosides of next generation: Synthesis of 4-(3-chloropropoxy)phenyl and 4-(3-azidopropoxy)phenyl glycosides; Carbohydrate Research; Vol. 471

Janus glycosides of next generation: Synthesis of 4-(3-chloropropoxy)phenyl and 4-(3-azidopropoxy)phenyl glycosides; Carbohydrate Research; Vol. 471

Bibliographic Details
Parent link:Carbohydrate Research
Vol. 471.— 2019.— [P. 95-104]
Corporate Author: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий (ИШХБМТ)
Other Authors: Stepanova E. V. Elena Vladimirovna, Abronina P. I. Polina Igorevna, Zinin A. I. Aleksandr Ivanovich, Chizhov A. O. Aleksandr Olegovich, Kononov L. O. Leonid Olegovich
Summary:Title screen
Efficient procedures for the preparative synthesis of per-O-acyl derivatives of 4-(3-chloropropoxy)phenyl (CPP) glycosides of a series of common mono- and disaccharides (d-glucose, d-galactose, d-mannose, l-rhamnose, d-arabinofuranose, d-glucosamine, lactose) are described. The CPP glycosides obtained were transformed in almost quantitative yields to the corresponding unprotected 4-(3-azidopropoxy)phenyl (APP) glycosides, which could become next-generation Janus glycosides with cleavable spacer aglycon, ready for conjugation or further transformation.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2019
Subjects:
электронный ресурс
труды учёных ТПУ
glycosylation
spacer aglycon
janus aglycon
cleavable aglycon
гликозилирование
агликоны
Online Access:https://doi.org/10.1016/j.carres.2018.11.013
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=659366

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