Janus glycosides of next generation: Synthesis of 4-(3-chloropropoxy)phenyl and 4-(3-azidopropoxy)phenyl glycosides

Bibliographic Details
Parent link:Carbohydrate Research
Vol. 471.— 2019.— [P. 95-104]
Corporate Author: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий (ИШХБМТ)
Other Authors: Stepanova E. V. Elena Vladimirovna, Abronina P. I. Polina Igorevna, Zinin A. I. Aleksandr Ivanovich, Chizhov A. O. Aleksandr Olegovich, Kononov L. O. Leonid Olegovich
Summary:Title screen
Efficient procedures for the preparative synthesis of per-O-acyl derivatives of 4-(3-chloropropoxy)phenyl (CPP) glycosides of a series of common mono- and disaccharides (d-glucose, d-galactose, d-mannose, l-rhamnose, d-arabinofuranose, d-glucosamine, lactose) are described. The CPP glycosides obtained were transformed in almost quantitative yields to the corresponding unprotected 4-(3-azidopropoxy)phenyl (APP) glycosides, which could become next-generation Janus glycosides with cleavable spacer aglycon, ready for conjugation or further transformation.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2019
Subjects:
Online Access:https://doi.org/10.1016/j.carres.2018.11.013
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=659366

MARC

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200 1 |a Janus glycosides of next generation: Synthesis of 4-(3-chloropropoxy)phenyl and 4-(3-azidopropoxy)phenyl glycosides  |f E. V. Stepanova [et al.] 
203 |a Text  |c electronic 
300 |a Title screen 
320 |a [References: 77 tit.] 
330 |a Efficient procedures for the preparative synthesis of per-O-acyl derivatives of 4-(3-chloropropoxy)phenyl (CPP) glycosides of a series of common mono- and disaccharides (d-glucose, d-galactose, d-mannose, l-rhamnose, d-arabinofuranose, d-glucosamine, lactose) are described. The CPP glycosides obtained were transformed in almost quantitative yields to the corresponding unprotected 4-(3-azidopropoxy)phenyl (APP) glycosides, which could become next-generation Janus glycosides with cleavable spacer aglycon, ready for conjugation or further transformation. 
333 |a Режим доступа: по договору с организацией-держателем ресурса 
461 |t Carbohydrate Research 
463 |t Vol. 471  |v [P. 95-104]  |d 2019 
610 1 |a электронный ресурс 
610 1 |a труды учёных ТПУ 
610 1 |a glycosylation 
610 1 |a spacer aglycon 
610 1 |a janus aglycon 
610 1 |a cleavable aglycon 
610 1 |a гликозилирование 
610 1 |a агликоны 
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701 1 |a Abronina  |b P. I.  |g Polina Igorevna 
701 1 |a Zinin  |b A. I.  |g Aleksandr Ivanovich 
701 1 |a Chizhov  |b A. O.  |g Aleksandr Olegovich 
701 1 |a Kononov  |b L. O.  |g Leonid Olegovich 
712 0 2 |a Национальный исследовательский Томский политехнический университет  |b Исследовательская школа химических и биомедицинских технологий (ИШХБМТ)  |c (2017- )  |3 (RuTPU)RU\TPU\col\23537 
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