Porous Inorganic Carriers Based on Silica, Calcium Carbonate and Calcium Phosphate for Controlled/Modulated Drug Delivery: Fresh Outlook and Future Perspectives; Pharmaceutics; Vol. 10, iss. 4

Bibliografiske detaljer
Parent link:Pharmaceutics
Vol. 10, iss. 4.— 2018.— [167, 35 p.]
Institution som forfatter: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий (ИШХБМТ)
Andre forfattere: Trofimov A. D. Aleksey, Ivanova A. A. Anna Aleksandrovna, Zyuzin M. V. Mikhail, Timin M. V. Mikhail
Summary:Title screen
Porous inorganic nanostructured materials are widely used nowadays as drug delivery carriers due to their adventurous features: suitable architecture, large surface area and stability in the biological fluids. Among the different types of inorganic porous materials, silica, calcium carbonate, and calcium phosphate have received significant attention in the last decade. The use of porous inorganic materials as drug carriers for cancer therapy, gene delivery etc. has the potential to improve the life expectancy of the patients affected by the disease. The main goal of this review is to provide general information on the current state of the art of synthesis of the inorganic porous particles based on silica, calcium carbonate and calcium phosphate. Special focus is dedicated to the loading capacity, controllable release of drugs under internal biological stimuli (e.g., pH, redox, enzymes) and external noninvasive stimuli (e.g., light, magnetic field, and ultrasound). Moreover, the diverse compounds to deliver with silica, calcium carbonate and calcium phosphate particles, ranging from the commercial drugs to genetic materials are also discussed.
Sprog:engelsk
Udgivet: 2018
Fag:
Online adgang:http://earchive.tpu.ru/handle/11683/64945
https://doi.org/10.3390/pharmaceutics10040167
Format: Electronisk Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=658972

MARC

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200 1 |a Porous Inorganic Carriers Based on Silica, Calcium Carbonate and Calcium Phosphate for Controlled/Modulated Drug Delivery: Fresh Outlook and Future Perspectives  |f A. D. Trofimov [et al.] 
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300 |a Title screen 
320 |a [References: р. 26-35 (197 tit.)] 
330 |a Porous inorganic nanostructured materials are widely used nowadays as drug delivery carriers due to their adventurous features: suitable architecture, large surface area and stability in the biological fluids. Among the different types of inorganic porous materials, silica, calcium carbonate, and calcium phosphate have received significant attention in the last decade. The use of porous inorganic materials as drug carriers for cancer therapy, gene delivery etc. has the potential to improve the life expectancy of the patients affected by the disease. The main goal of this review is to provide general information on the current state of the art of synthesis of the inorganic porous particles based on silica, calcium carbonate and calcium phosphate. Special focus is dedicated to the loading capacity, controllable release of drugs under internal biological stimuli (e.g., pH, redox, enzymes) and external noninvasive stimuli (e.g., light, magnetic field, and ultrasound). Moreover, the diverse compounds to deliver with silica, calcium carbonate and calcium phosphate particles, ranging from the commercial drugs to genetic materials are also discussed. 
461 1 |t Pharmaceutics 
463 1 |t Vol. 10, iss. 4  |v [167, 35 p.]  |d 2018 
610 1 |a электронный ресурс 
610 1 |a труды учёных ТПУ 
610 1 |a drug delivery systems 
610 1 |a silica-based particles 
610 1 |a calcium carbonate 
610 1 |a calcium phosphate 
610 1 |a in vitro and in vivo delivery 
610 1 |a drug loading 
610 1 |a доставка 
610 1 |a лекарства 
610 1 |a кремнеземы 
610 1 |a карбонат кальция 
610 1 |a фосфат кальция 
701 1 |a Trofimov  |b A. D.  |g Aleksey 
701 1 |a Ivanova  |b A. A.  |c physicist  |c engineer-researcher of Tomsk Polytechnic University  |f 1986-  |g Anna Aleksandrovna  |3 (RuTPU)RU\TPU\pers\34747 
701 1 |a Zyuzin  |b M. V.  |g Mikhail 
701 1 |a Timin  |b M. V.  |g Mikhail 
712 0 2 |a Национальный исследовательский Томский политехнический университет  |b Исследовательская школа химических и биомедицинских технологий (ИШХБМТ)  |c (2017- )  |3 (RuTPU)RU\TPU\col\23537 
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