Electrochemical oxidability of antioxidants: Synergism and antagonism in mixes; Journal of Pharmacy and Bioallied Sciences; Vol. 10, iss. 2
| Parent link: | Journal of Pharmacy and Bioallied Sciences Vol. 10, iss. 2.— 2018.— [P. 60-65] |
|---|---|
| 企业作者: | |
| 其他作者: | , , , , |
| 总结: | Title screen To investigate electrochemical oxidability of antioxidants to reveal synergistic and antagonistic effects in mixes. Materials and Methods: Electrochemical oxidability of some widely used antioxidants, including uric acid, glutathione, trolox, ascorbic acid, gallic acid, Mexidol, and potassium fenozan, was investigated by the amperometric approach. Results: All obtained electrochemical oxidability values correlate well with antioxidant activity parameters of the same compounds measured by other methods. The measurements of the electrochemical oxidability for binary mixes of substances were tested to reveal any synergistic actions. The experimental results and calculated values overlap for various combinations of tested mixes. It testifies to the absence of interaction between them (both synergism and antagonism) in the oxidation process. Conclusions: The constants of oxidation were defined for different antioxidants and mixes by amperometric approach. Most mixes of probed compounds revealed absence of interaction between them in oxidation process. In some cases (mainly with glutathione and ascorbic acid), antagonism takes place, deteriorating effects of their joint application. Apparently, a partial reduction of glutathione by ascorbic acid leads to excess of the measured value over calculated value. Режим доступа: по договору с организацией-держателем ресурса |
| 语言: | 英语 |
| 出版: |
2018
|
| 主题: | |
| 在线阅读: | http://dx.doi.org/10.4103/JPBS.JPBS_203_17 |
| 格式: | MixedMaterials 电子 本书章节 |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=658830 |
MARC
| LEADER | 00000naa0a2200000 4500 | ||
|---|---|---|---|
| 001 | 658830 | ||
| 005 | 20250217143307.0 | ||
| 035 | |a (RuTPU)RU\TPU\network\26954 | ||
| 090 | |a 658830 | ||
| 100 | |a 20181129d2018 k||y0rusy50 ba | ||
| 101 | 0 | |a eng | |
| 135 | |a drcn ---uucaa | ||
| 181 | 0 | |a i | |
| 182 | 0 | |a b | |
| 200 | 1 | |a Electrochemical oxidability of antioxidants: Synergism and antagonism in mixes |f N. N. Sazhina [et al.] | |
| 203 | |a Text |c electronic | ||
| 300 | |a Title screen | ||
| 320 | |a [References: 29 tit.] | ||
| 330 | |a To investigate electrochemical oxidability of antioxidants to reveal synergistic and antagonistic effects in mixes. Materials and Methods: Electrochemical oxidability of some widely used antioxidants, including uric acid, glutathione, trolox, ascorbic acid, gallic acid, Mexidol, and potassium fenozan, was investigated by the amperometric approach. Results: All obtained electrochemical oxidability values correlate well with antioxidant activity parameters of the same compounds measured by other methods. The measurements of the electrochemical oxidability for binary mixes of substances were tested to reveal any synergistic actions. The experimental results and calculated values overlap for various combinations of tested mixes. It testifies to the absence of interaction between them (both synergism and antagonism) in the oxidation process. Conclusions: The constants of oxidation were defined for different antioxidants and mixes by amperometric approach. Most mixes of probed compounds revealed absence of interaction between them in oxidation process. In some cases (mainly with glutathione and ascorbic acid), antagonism takes place, deteriorating effects of their joint application. Apparently, a partial reduction of glutathione by ascorbic acid leads to excess of the measured value over calculated value. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
| 461 | 1 | |t Journal of Pharmacy and Bioallied Sciences | |
| 463 | 1 | |t Vol. 10, iss. 2 |v [P. 60-65] |d 2018 | |
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a амперометрия | |
| 610 | 1 | |a антагонизм | |
| 610 | 1 | |a антиоксиданты | |
| 610 | 1 | |a синергизм | |
| 701 | 1 | |a Sazhina |b N. N. |g Nataljya | |
| 701 | 1 | |a Plotnikov |b E. V. |c chemist |c Associate Professor of Tomsk Polytechnic University, Candidate of Chemical Sciences |f 1983- |g Evgeny Vladimirovich |3 (RuTPU)RU\TPU\pers\32469 |9 16417 | |
| 701 | 1 | |a Korotkova |b E. I. |c chemist |c Professor of Tomsk Polytechnic University, Doctor of chemical science |f 1965- |g Elena Ivanovna |3 (RuTPU)RU\TPU\pers\31278 |9 15456 | |
| 701 | 1 | |a Dorozhko |b E. V. |c chemist |c Engineer of Tomsk Polytechnic University |f 1979- |g Elena Vladimirovna |3 (RuTPU)RU\TPU\pers\32174 |9 16175 | |
| 701 | 1 | |a Voronova |b O. A. |c chemist |c Assistant of Tomsk Polytechnic University, Candidate of chemical sciences |f 1979- |g Olesya Aleksandrovna |3 (RuTPU)RU\TPU\pers\32169 |9 16170 | |
| 712 | 0 | 2 | |a Национальный исследовательский Томский политехнический университет |b Инженерная школа природных ресурсов |b Отделение химической инженерии |3 (RuTPU)RU\TPU\col\23513 |
| 801 | 2 | |a RU |b 63413507 |c 20181129 |g RCR | |
| 856 | 4 | |u http://dx.doi.org/10.4103/JPBS.JPBS_203_17 | |
| 942 | |c CF | ||