Development and Study of {99m}Tc-1-Thio-D-glucose for Visualization of Malignant Tumors

Development and Study of {99m}Tc-1-Thio-D-glucose for Visualization of Malignant Tumors

Bibliographic Details
Parent link:AIP Conference Proceedings
Vol. 1882 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications (PC IPCA’17).— 2017.— [020083, 6 p.]
Other Authors: Zelchan (Zeltchan) R. V. Roman Vladimirovich, Medvedeva А. А. Anna Aleksandrovna, Sinilkin I. G. Ivan Gennadjevich, Bragina O. D. Olga Dmitrievna, Chernov V. I. Vladimir Ivanovich, Stasyuk (Stasiuk) E. S. Elena Sergeyevna, Rogov A. S. Alexander Sergeyevich, Ilina E. S. Elena Sergeevna, Skuridin V. S. Viktor Sergeyevich
Summary:Title screen
The preclinical studies of {99m}Tc-1-Thio-D-glucose, a new tumor-seeking agent based on technetium-99mlabeled glucose derivative, were conducted, and the feasibility of using this radiopharmaceutical for tumor visualization was studied. The preclinical studies were carried out strictly in accordance with the local legislation and were regulated by the generally accepted research standards. {99m}Tc-1-Thio-D-glucose was found to have optimal pharmacokinetic and physico-chemical properties for diagnostic imaging and was proved to belong to the low-toxic substances. The potential utility of {99m}Tc-1-thio-D-glucose for tumor imaging was studied in vitro and in vivo models. The present study demonstrated that {99m}Tc-1-Thio-D-glucose is a prospective radiopharmaceutical for cancer visualization.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2017
Subjects:
электронный ресурс
труды учёных ТПУ
визуализация
злокачественные опухоли
радиофармацевтические препараты
физико-химические свойства
рак
Online Access:https://doi.org/10.1063/1.5001662
http://earchive.tpu.ru/handle/11683/46892
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=657749

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