Development and Study of {99m}Tc-1-Thio-D-glucose for Visualization of Malignant Tumors
| Parent link: | AIP Conference Proceedings Vol. 1882 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications (PC IPCA’17).— 2017.— [020083, 6 p.] |
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| Drugi avtorji: | , , , , , , , , |
| Izvleček: | Title screen The preclinical studies of {99m}Tc-1-Thio-D-glucose, a new tumor-seeking agent based on technetium-99mlabeled glucose derivative, were conducted, and the feasibility of using this radiopharmaceutical for tumor visualization was studied. The preclinical studies were carried out strictly in accordance with the local legislation and were regulated by the generally accepted research standards. {99m}Tc-1-Thio-D-glucose was found to have optimal pharmacokinetic and physico-chemical properties for diagnostic imaging and was proved to belong to the low-toxic substances. The potential utility of {99m}Tc-1-thio-D-glucose for tumor imaging was studied in vitro and in vivo models. The present study demonstrated that {99m}Tc-1-Thio-D-glucose is a prospective radiopharmaceutical for cancer visualization. Режим доступа: по договору с организацией-держателем ресурса |
| Jezik: | angleščina |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://doi.org/10.1063/1.5001662 http://earchive.tpu.ru/handle/11683/46892 |
| Format: | Elektronski Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=657749 |
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| 200 | 1 | |a Development and Study of {99m}Tc-1-Thio-D-glucose for Visualization of Malignant Tumors |f R. V. Zelchan (Zeltchan), А. А. Medvedeva, I. G. Sinilkin [et al.] | |
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| 300 | |a Title screen | ||
| 320 | |a [References: 5 tit.] | ||
| 330 | |a The preclinical studies of {99m}Tc-1-Thio-D-glucose, a new tumor-seeking agent based on technetium-99mlabeled glucose derivative, were conducted, and the feasibility of using this radiopharmaceutical for tumor visualization was studied. The preclinical studies were carried out strictly in accordance with the local legislation and were regulated by the generally accepted research standards. {99m}Tc-1-Thio-D-glucose was found to have optimal pharmacokinetic and physico-chemical properties for diagnostic imaging and was proved to belong to the low-toxic substances. The potential utility of {99m}Tc-1-thio-D-glucose for tumor imaging was studied in vitro and in vivo models. The present study demonstrated that {99m}Tc-1-Thio-D-glucose is a prospective radiopharmaceutical for cancer visualization. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
| 461 | 0 | |0 (RuTPU)RU\TPU\network\4816 |t AIP Conference Proceedings | |
| 463 | 0 | |0 (RuTPU)RU\TPU\network\24427 |t Vol. 1882 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications (PC IPCA’17) |o Proceedings of the International conference, 23–26 May 2017, Tomsk, Russia |f National Research Tomsk Polytechnic University (TPU) ; eds. E. Y. Gutmanas, O. B. Naimark, Yu. P. Sharkeev |v [020083, 6 p.] |d 2017 | |
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| 610 | 1 | |a злокачественные опухоли | |
| 610 | 1 | |a радиофармацевтические препараты | |
| 610 | 1 | |a физико-химические свойства | |
| 610 | 1 | |a рак | |
| 701 | 1 | |a Zelchan (Zeltchan) |b R. V. |c specialist in the field of medical technology |c Researcher of the Tomsk Polytechnic University, Candidate of Medical Sciences |f 1984- |g Roman Vladimirovich |3 (RuTPU)RU\TPU\pers\34194 |9 17728 | |
| 701 | 1 | |a Medvedeva |b А. А. |g Anna Aleksandrovna |f 1975- |c specialist in the field of medical technology |c research fellow of Tomsk Polytechnic University, Doctor of Medical Sciences |3 (RuTPU)RU\TPU\pers\37376 |9 20294 | |
| 701 | 1 | |a Sinilkin |b I. G. |c specialist in the field of medical technology |c laboratory, Tomsk Polytechnic University, candidate of medical science |f 1972- |g Ivan Gennadjevich |3 (RuTPU)RU\TPU\pers\34189 |9 17723 | |
| 701 | 1 | |a Bragina |b O. D. |c specialist in the field of medical technology |c Senior Researcher of the Tomsk Polytechnic University, Doctor of Medical Sciences |f 1986- |g Olga Dmitrievna |y Tomsk |3 (RuTPU)RU\TPU\pers\35943 |9 19084 | |
| 701 | 1 | |a Chernov |b V. I. |c specialist in the field of medical technology |c lead engineer of Tomsk Polytechnic University, doctor of medical sciences |f 1962- |g Vladimir Ivanovich |3 (RuTPU)RU\TPU\pers\34191 |9 17725 | |
| 701 | 1 | |a Stasyuk (Stasiuk) |b E. S. |c Specialist in the field of nuclear power engineering |c Researcher of Tomsk Polytechnic University, Candidate of technical sciences |f 1978- |g Elena Sergeyevna |3 (RuTPU)RU\TPU\pers\32656 |9 16555 | |
| 701 | 1 | |a Rogov |b A. S. |c Radiochemist |c Engineer of Tomsk Polytechnic University |f 1986- |g Alexander Sergeyevich |3 (RuTPU)RU\TPU\pers\32658 |9 16557 | |
| 701 | 1 | |a Ilina |b E. S. |c engineer Tomsk Polytechnic University |c Chemical Engineer |f 1989- |g Elena Sergeevna |3 (RuTPU)RU\TPU\pers\32758 |9 16636 | |
| 701 | 1 | |a Skuridin |b V. S. |c Physicist, Specialist in the field of nuclear power engineering |c Professor of Tomsk Polytechnic University, Doctor of technical sciences |f 1946- |g Viktor Sergeyevich |3 (RuTPU)RU\TPU\pers\32655 |9 16554 | |
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