Two-Dimensional Al Hydroxide Interaction with Cancerous Cell Membrane Building Units: Complexed Free Energy and Orientation Analysis; AIP Conference Proceedings; Vol. 1882 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications (PC IPCA’17)
| Parent link: | AIP Conference Proceedings Vol. 1882 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications (PC IPCA’17).— 2017.— [020076, 5 p.] |
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| প্রধান লেখক: | |
| সংস্থা লেখক: | |
| অন্যান্য লেখক: | |
| সংক্ষিপ্ত: | Title screen The application of hierarchical nanoparticles based on metal hydroxides in biomedicine, including anticancer therapy and medical imaging, is a rapidly developing field. Low-dimensional aluminum oxyhydroxide nanomaterials (AlOOH-NM) are quite promising base to develop hybrid theranostic nano-agents with core-shell architecture, which is determined by AlOOH-NMs physicochemical properties such as: large specific surface area, pH-dependent charge, amphoteric behavior, high surface density of polar groups capable to form non-covalent bonds, low or null cytotoxicity and biocompatibility. Characterization of the system behavior within interface between NM and plasmatic membrane is crucial for the understanding of nano-agent-cell interaction. In the present work the complex in silico study including the free energy estimation and orientation analysis of phosphatidylcholine (POPC) and phosphatidylethanolamine (POPE) lipids interacting with AlOOH nanosheet was conducted to understand the effect of such nanomaterial on cancerous cell plasmatic membrane. Режим доступа: по договору с организацией-держателем ресурса |
| ভাষা: | ইংরেজি |
| প্রকাশিত: |
2017
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://doi.org/10.1063/1.5001655 http://earchive.tpu.ru/handle/11683/46891 |
| বিন্যাস: | বৈদ্যুতিক গ্রন্থের অধ্যায় |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=657748 |
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| 200 | 1 | |a Two-Dimensional Al Hydroxide Interaction with Cancerous Cell Membrane Building Units: Complexed Free Energy and Orientation Analysis |f A. A. Tsukanov, S. G. Psakhie | |
| 203 | |a Text |c electronic | ||
| 300 | |a Title screen | ||
| 320 | |a [References: 26 tit.] | ||
| 330 | |a The application of hierarchical nanoparticles based on metal hydroxides in biomedicine, including anticancer therapy and medical imaging, is a rapidly developing field. Low-dimensional aluminum oxyhydroxide nanomaterials (AlOOH-NM) are quite promising base to develop hybrid theranostic nano-agents with core-shell architecture, which is determined by AlOOH-NMs physicochemical properties such as: large specific surface area, pH-dependent charge, amphoteric behavior, high surface density of polar groups capable to form non-covalent bonds, low or null cytotoxicity and biocompatibility. Characterization of the system behavior within interface between NM and plasmatic membrane is crucial for the understanding of nano-agent-cell interaction. In the present work the complex in silico study including the free energy estimation and orientation analysis of phosphatidylcholine (POPC) and phosphatidylethanolamine (POPE) lipids interacting with AlOOH nanosheet was conducted to understand the effect of such nanomaterial on cancerous cell plasmatic membrane. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
| 461 | 0 | |0 (RuTPU)RU\TPU\network\4816 |t AIP Conference Proceedings | |
| 463 | 0 | |0 (RuTPU)RU\TPU\network\24427 |t Vol. 1882 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications (PC IPCA’17) |o Proceedings of the International conference, 23–26 May 2017, Tomsk, Russia |f National Research Tomsk Polytechnic University (TPU) ; eds. E. Y. Gutmanas, O. B. Naimark, Yu. P. Sharkeev |v [020076, 5 p.] |d 2017 | |
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a гидроксид алюминия | |
| 610 | 1 | |a рак | |
| 610 | 1 | |a наночастицы | |
| 610 | 1 | |a биомедицина | |
| 610 | 1 | |a противоопухолевая терапия | |
| 610 | 1 | |a медицинская визуализация | |
| 610 | 1 | |a физико-химические свойства | |
| 610 | 1 | |a цитотоксичность | |
| 610 | 1 | |a биосовместимость | |
| 610 | 1 | |a раковые клетки | |
| 700 | 1 | |a Tsukanov |b A. A. |c physicist |c researcher of Tomsk Polytechnic University, candidate of physical and mathematical sciences |f 1984- |g Aleksey Alekseevich |2 stltpush |3 (RuTPU)RU\TPU\pers\35787 | |
| 701 | 1 | |a Psakhie |b S. G. |c physicist |c head of laboratory, Advisor to the rector, head of Department, Tomsk Polytechnic University, doctor of physico-mathematical Sciences |f 1952- |g Sergey Grigorievich |2 stltpush |3 (RuTPU)RU\TPU\pers\33038 | |
| 712 | 0 | 2 | |a Национальный исследовательский Томский политехнический университет |b Инженерная школа новых производственных технологий |b Отделение материаловедения |h 7871 |2 stltpush |3 (RuTPU)RU\TPU\col\23508 |
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