Biological-Based and Physical-Based Optimization for Biological Evaluation of Prostate Patient's Plans; AIP Conference Proceedings; Vol. 1882 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications (PC IPCA’17)

Dettagli Bibliografici
Parent link:AIP Conference Proceedings
Vol. 1882 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications (PC IPCA’17).— 2017.— [020074, 4 p.]
Autore principale: Sukhikh E. S. Evgeniya Sergeevna
Ente Autore: Национальный исследовательский Томский политехнический университет Инженерная школа ядерных технологий Отделение ядерно-топливного цикла
Altri autori: Sheino I., Vertinsky A.
Riassunto:Title screen
Modern modalities of radiation treatment therapy allow irradiation of the tumor to high dose values and irradiation of organs at risk (OARs) to low dose values at the same time. In this paper we study optimal radiation treatment plans made in Monaco system. The first aim of this study was to evaluate dosimetric features of Monaco treatment planning system using biological versus dose-based cost functions for the OARs and irradiation targets (namely tumors) when the full potential of built-in biological cost functions is utilized. The second aim was to develop criteria for the evaluation of radiation dosimetry plans for patients based on the macroscopic radiobiological criteria - TCP/NTCP. In the framework of the study four dosimetric plans were created utilizing the full extent of biological and physical cost functions using dose calculation-based treatment planning for IMRT Step-and-Shoot delivery of stereotactic body radiation therapy (SBRT) in prostate case (5 fractions per 7 Gy).
Режим доступа: по договору с организацией-держателем ресурса
Lingua:inglese
Pubblicazione: 2017
Soggetti:
Accesso online:https://doi.org/10.1063/1.5001653
http://earchive.tpu.ru/handle/11683/46889
Natura: Elettronico Capitolo di libro
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=657747

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330 |a Modern modalities of radiation treatment therapy allow irradiation of the tumor to high dose values and irradiation of organs at risk (OARs) to low dose values at the same time. In this paper we study optimal radiation treatment plans made in Monaco system. The first aim of this study was to evaluate dosimetric features of Monaco treatment planning system using biological versus dose-based cost functions for the OARs and irradiation targets (namely tumors) when the full potential of built-in biological cost functions is utilized. The second aim was to develop criteria for the evaluation of radiation dosimetry plans for patients based on the macroscopic radiobiological criteria - TCP/NTCP. In the framework of the study four dosimetric plans were created utilizing the full extent of biological and physical cost functions using dose calculation-based treatment planning for IMRT Step-and-Shoot delivery of stereotactic body radiation therapy (SBRT) in prostate case (5 fractions per 7 Gy). 
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