Surface modification of electrospun poly-(l-lactic) acid scaffolds by reactive magnetron sputtering

Surface modification of electrospun poly-(l-lactic) acid scaffolds by reactive magnetron sputtering

Bibliographic Details
Parent link:Colloids and Surfaces B: Biointerfaces
Vol. 162.— 2018.— [P. 43-51]
Corporate Authors: Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Кафедра экспериментальной физики (ЭФ), Национальный исследовательский Томский политехнический университет (ТПУ) Институт физики высоких технологий (ИФВТ) Кафедра биотехнологии и органической химии (БИОХ)
Other Authors: Bolbasov E. N. Evgeny Nikolaevich, Marjin (Maryin) P. V. Pavel Vladimirovich, Stankevich K. S. Ksenia Sergeevna, Kozelskaya A. I. Anna Ivanovna, Shesterikov E. V. Evgeny Viktorovich, Khodyrevskaya Y. I. Yuliya Ivanovna, Nasonova M. V. Marina Vladimirovna, Shishkova D. K. Darjya Kirillovna, Kudryavtseva Y. A. Yuliya Aleksandrovna, Anissimov Y. G. Yuri, Tverdokhlebov S. I. Sergei Ivanovich
Summary:Title screen
In this study, we modified the surface of bioresorbable electrospun poly-(l-lactic) acid (PLLA) scaffolds by reactive magnetron sputtering of a titanium target under a nitrogen atmosphere. We examined the influence ofthe plasma treatmenttime on the structure and properties of electrospun PLLAscaffolds using SEM, XRF, FTIR, XRD, optical goniometry, and mechanical testing. It was observed that the coating formed didnot changephysicomechanicalproperties of electrospunPLLAscaffolds and simultaneously,increased their hydrophilicity. No adverse tissue reaction up to 3 months after subcutaneous implantation of the modified scaffolds was detected in in-vivo rat model. The rate of scaffold replacement by the recipient tissue in-vivo was observed to depend on the plasma treatment time.
Режим доступа: по договору с организацией-держателем ресурса
Published: 2018
Subjects:
электронный ресурс
труды учёных ТПУ
реактивное магнетронное распыление
биосовместимость
скаффолды
ИК-Фурье спектроскопия
дифракция
Online Access:https://doi.org/10.1016/j.colsurfb.2017.11.028
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=657334

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