In Vitro Assessment of Hydroxyapatite Coating on the Surface of Additive Manufactured Ti6Al4V Scaffolds

In Vitro Assessment of Hydroxyapatite Coating on the Surface of Additive Manufactured Ti6Al4V Scaffolds

Bibliographic Details
Parent link:Materials Science Forum
Vol. 879 : THERMEC 2016.— 2017.— [P. 2444-2449]
Corporate Authors: Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Кафедра общей физики (ОФ), Национальный исследовательский Томский политехнический университет (ТПУ) Инженерная школа ядерных технологий (ИЯТШ) Лаборатория плазменных гибридных систем (ЛПГС)
Other Authors: Chudinova E. A. Ekaterina Aleksandrovna, Surmeneva M. A. Maria Alexandrovna, Koptioug A. V. Andrei, Savintseva I. V. Irina Viktorovna, Selezneva I. V. Irina Ivanovna, Skoglund P. Per, Syrtanov M. S. Maksim Sergeevich, Surmenev R. A. Roman Anatolievich
Summary:Title screen
Custom orthopedic and dental implants may be fabricated by additive manufacturing (AM), for example using electron beam melting technology. This study is focused on the modification of the surface of Ti6Al4V alloy coin-like scaffolds fabricated via AM technology (EBM®) by radio frequency (RF) magnetron sputter deposition of hydroxyapatite (HA) coating. The scaffolds with HA coating were characterized by Scanning Electron microscopy, X-ray diffraction. HA coating showed a nanocrystalline structure with the crystallites of an average size of 32±9 nm. The ability of the surface to support adhesion and the proliferation of human mesenchymal stem cells was studied using biological short-term tests in vitro. In according to in vitro assessment, thin HA coating stimulated the attachment and proliferation of cells. Human mesenchymal stem cells cultured on the HA-coated scaffold also formed mineralized.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2017
Subjects:
электронный ресурс
труды учёных ТПУ
гидроксиапатиты
аддитивное производство
Online Access:http://dx.doi.org/10.4028/www.scientific.net/MSF.879.2444
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=656857
Description
Summary:Title screen
Custom orthopedic and dental implants may be fabricated by additive manufacturing (AM), for example using electron beam melting technology. This study is focused on the modification of the surface of Ti6Al4V alloy coin-like scaffolds fabricated via AM technology (EBM®) by radio frequency (RF) magnetron sputter deposition of hydroxyapatite (HA) coating. The scaffolds with HA coating were characterized by Scanning Electron microscopy, X-ray diffraction. HA coating showed a nanocrystalline structure with the crystallites of an average size of 32±9 nm. The ability of the surface to support adhesion and the proliferation of human mesenchymal stem cells was studied using biological short-term tests in vitro. In according to in vitro assessment, thin HA coating stimulated the attachment and proliferation of cells. Human mesenchymal stem cells cultured on the HA-coated scaffold also formed mineralized.
Режим доступа: по договору с организацией-держателем ресурса
DOI:10.4028/www.scientific.net/MSF.879.2444

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