Cell-IQ visualization of motility, cell mass, and osteogenic differentiation of multipotent mesenchymal stromal cells cultured with relief calcium phosphate coating; Doklady Biochemistry and Biophysics; Vol. 476, iss. 1

Cell-IQ visualization of motility, cell mass, and osteogenic differentiation of multipotent mesenchymal stromal cells cultured with relief calcium phosphate coating; Doklady Biochemistry and Biophysics; Vol. 476, iss. 1

Dettagli Bibliografici
Parent link:Doklady Biochemistry and Biophysics
Vol. 476, iss. 1.— 2017.— [P. 310–315]
Enti autori: Национальный исследовательский Томский политехнический университет (ТПУ) Институт природных ресурсов (ИПР) Кафедра физической и аналитической химии (ФАХ), Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Кафедра экспериментальной физики (ЭФ)
Altri autori: Litvinova L. S., Shupletsova V. V., Yurova K. A., Khaziakhmatova O. G., Todosenko N. M., Khlusova M. Yu., Slepchenko G. B. Galina Borisovna, Cherempey E. G. Elena Gennadjevna, Sharkeev Yu. P. Yury Petrovich, Komarova E. G. Elena Gennadjevna, Sedelnikova M. B. Mariya Borisovna, Malashenko V. V., Melashchenko E. S., Khlusov I. A. Igor Albertovich
Riassunto:Title screen
The Cell-IQ continuous surveillance system allowed us to establish the following changes in a 14- day culture in vitro: a twofold suppression of the directional migration of multipotent mesenchymal stromal cells of human adipose tissue (MMSC-AT) towards the samples with a microarc calcium phosphate (CP) coating from synthetic hydroxyapatite; a tenfold decrease in the cell mass on the interphase with the samples, which was accompanied by a slight reduction in the expression of membrane determinants of stromal stem cells; and an enhancement of their osteogenic differentiation (osteocalcin secretion and mineralized matrix formation) on the 21st day of the study. Calcium phosphate particles, but not the calcium and phosphorus ions, may trigger the phenotypic transformation of the MMSC-AT behavior in vitro.
Режим доступа: по договору с организацией-держателем ресурса
Lingua:inglese
Pubblicazione: 2017
Serie:Biochemistry, Biophysics, and Molecular Biology
Soggetti:
труды учёных ТПУ
электронный ресурс
биоинженерия
костная ткань
фосфатное покрытие
Accesso online:https://doi.org/10.1134/S1607672917050076
Natura: Elettronico Capitolo di libro
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=656617

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