Voltammetric determination of cholesterol in human blood serum; Journal of Analytical Chemistry; Vol. 72, iss. 8

Voltammetric determination of cholesterol in human blood serum; Journal of Analytical Chemistry; Vol. 72, iss. 8

Bibliographic Details
Parent link:Journal of Analytical Chemistry
Vol. 72, iss. 8.— 2017.— [P. 904–910]
Corporate Author: Национальный исследовательский Томский политехнический университет (ТПУ) Институт природных ресурсов (ИПР) Кафедра физической и аналитической химии (ФАХ)
Other Authors: Derina K. V. Kseniya Vladimirovna, Korotkova E. I. Elena Ivanovna, Dorozhko E. V. Elena Vladimirovna, Voronova O. A. Olesya Aleksandrovna
Summary:Title screen
Cholesterol has a number of important functions in a human body. The disorders of cholesterol biosynthesis increase the risk of the development of cardiovascular diseases and worsens the function of the immune system. This study is devoted to the development of a method for determining the concentration of cholesterol in blood serum using voltammetry. We selected the following working conditions for the determination of cholesterol: a phosphate buffer solution with pH 6.86 was a supporting electrolyte; potential sweep rate was W = 30 mV/s; and recording was carried out in the constant-current mode. An organomodified electrode was used as a working electrode. The peak was observed at +0.98 V. The dependence of the electrooxidation current of cholesterol on its concentration was linear in the range of 0.1–50 µM with a limit of detection of 0.01 µM. The results of the determination of cholesterol in blood serum by voltammetry were compared to those obtained by the fluorimetric method.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2017
Subjects:
труды учёных ТПУ
электронный ресурс
холестерин
сердечно-сосудистая система
сердечно-сосудистые заболевания
сыворотка крови
Online Access:https://doi.org/10.1134/S1061934817080068
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=656152

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