Studying the General Toxicity and Cumulative Properties of a Radiopharmaceutical Nanocolloid, 99mTc-Al2O3; Bulletin of Experimental Biology and Medicine; Vol. 161, iss. 3
| Parent link: | Bulletin of Experimental Biology and Medicine Vol. 161, iss. 3.— 2016.— [P. 371-373] |
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| Korporativna značnica: | |
| Drugi avtorji: | , , , , , , , , , , , , |
| Izvleček: | Title screen We studied toxicity of a new Russian radiopharmaceutical Nanocolloid, 99mTc-Al2O3. Tests for acute toxicity showed that this agent belongs to a class of moderate-toxicity substances and does not have cumulative properties. The evaluation of subchronic toxicity after subcutaneous injection of this product to rats (0.04, 0.2, and 0.4 ml/kg) and rabbits (0.02 and 0.2 ml/kg) for 7 days did not reveal changes in the general state, temperature, body weight, indices of the peripheral blood and bone marrow, functions of the heart, liver, kidneys, and nervous system, and morphological characteristics of the internal organs in animals. The drug does not produce a local irritant effect. Режим доступа: по договору с организацией-держателем ресурса |
| Jezik: | angleščina |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://doi.org/10.1007/s10517-016-3416-0 |
| Format: | xMaterials Elektronski Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=655916 |
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| 200 | 1 | |a Studying the General Toxicity and Cumulative Properties of a Radiopharmaceutical Nanocolloid, 99mTc-Al2O3 |f N. V. Varlamova [et al.] | |
| 203 | |a Text |c electronic | ||
| 300 | |a Title screen | ||
| 320 | |a [References: p. 373 (8 tit.)] | ||
| 330 | |a We studied toxicity of a new Russian radiopharmaceutical Nanocolloid, 99mTc-Al2O3. Tests for acute toxicity showed that this agent belongs to a class of moderate-toxicity substances and does not have cumulative properties. The evaluation of subchronic toxicity after subcutaneous injection of this product to rats (0.04, 0.2, and 0.4 ml/kg) and rabbits (0.02 and 0.2 ml/kg) for 7 days did not reveal changes in the general state, temperature, body weight, indices of the peripheral blood and bone marrow, functions of the heart, liver, kidneys, and nervous system, and morphological characteristics of the internal organs in animals. The drug does not produce a local irritant effect. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
| 461 | |t Bulletin of Experimental Biology and Medicine | ||
| 463 | |t Vol. 161, iss. 3 |v [P. 371-373] |d 2016 | ||
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| 701 | 1 | |a Churin |b A. A. |g Aleksey Aleksandrovich | |
| 701 | 1 | |a Fomina |b T. I. |g Tatjyana Ivanovna | |
| 701 | 1 | |a Ermolaeva |b L. A. |g Lyubov Aleksandrovna | |
| 701 | 1 | |a Vetoshkina |b T. V. |g Tatjyana Vladimirovna | |
| 701 | 1 | |a Dubskaya |b T. Yu. |g Tatjyana Yurjevna | |
| 701 | 1 | |a Lamzina |b T. Yu. |g Tatjyana Yurjevna | |
| 701 | 1 | |a Fedorova |b E. P. |g Elena Pavlovna | |
| 701 | 1 | |a Neupokoeva |b O. V. |g Oksana Vladimirovna | |
| 701 | 1 | |a Larionova |b L. A. |c specialist in the field of radiochemistry |c Senior researcher of Tomsk Polytechnic University |f 1946- |g Lyudmila Aleksandrovna |3 (RuTPU)RU\TPU\pers\36172 |9 19269 | |
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