Influence of Humic Acids Extracted from Peat by Different Methods on Functional Activity of Macrophages in Vitro

Bibliografiske detaljer
Parent link:Bulletin of Experimental Biology and Medicine
Vol. 162, iss. 6.— 2017.— [P. 741-745]
Institution som forfatter: Национальный исследовательский Томский политехнический университет (ТПУ) Институт природных ресурсов (ИПР) Кафедра технологии органических веществ и полимерных материалов (ТОВПМ)
Andre forfattere: Trofimova E. S. Ekaterina Sergeevna, Zykova M. V. Mariya Vladimirovna, Ligacheva A. A. Anastasiya Aleksandrovna, Sherstoboev E. Yu. Evgeny Yurjevich, Zhdanov V. V. Vadim Viktorovich, Belousov M. V. Mikhail Valerievich, Yusubov M. S. Mekhman Suleiman-Ogly (Suleimanovich), Krivoshchekov S. V. Sergey Vladimirovich, Danilets M. G. Marina, Dygai A. V. Alexandr Mikhaylovich
Summary:Title screen
We studied activation of macrophages with humic acids extracted from peat of large deposits in the Tomsk region by two extraction methods: by hydroxide or sodium pyrophosphate. Humic acid of lowland peat types containing large amounts of aromatic carbon, phenolic and alcohol groups, carbohydrate residues and ethers, irrespectively of the extraction methods contained LPS admixture that probably determines their activating properties. Humic acid of upland peat types characterized by high content of carbonyl, carboxyl, and ester groups enhance NO production and reduce arginase expression, but these effects were minimized when sodium hydroxide was used as an extraction solvent. Pyrophosphate samples of the upland peat types were characterized by aromaticity and diversity of functional groups and have a significant advantage because of they induce specific endotoxin-independent stimulating action on antigen presenting cells.
Режим доступа: по договору с организацией-держателем ресурса
Sprog:engelsk
Udgivet: 2017
Fag:
Online adgang:https://doi.org/10.1007/s10517-017-3702-5
Format: Electronisk Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=655891

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