10-Alkenylphenothiazines

Bibliografische gegevens
Parent link:Chemistry of Heterocyclic Compounds
Vol. 22, iss. 1.— 1986.— [P. 100-103]
Andere auteurs: Anfinogenov V. A., Napilkova O. A., Sirotkina E. E., Filimonov V. D. Viktor Dmitrievich, Ogorodnikov V. D.
Samenvatting:Title screen
A study was carried out on the isomerization of 10-allylphenothiazine (I) in DMSO by the action of t-BuOK, KOH and NaOH. The isomerization proceeds stereospecifically at room temperature by the action of t-BuOK at an elevated temperature by the action of KOH and NaOH to give cis-10-propenylphenothiazine (II). The effect of the t-BuOK concentration, temperature and reaction time on the isomeric composition of the 10-propenylphenothiazines formed was studied. Under conditions of kinetic control, I gives II, which isomerizes under the reaction conditions to give an equilibrium mixture of cis- and trans-10-propenyl-phenothiazine with 44-45% trans isomer III. The isomerization temperature has virtually no effect on the II/III isomer ratio.
Режим доступа: по договору с организацией-держателем ресурса
Taal:Engels
Gepubliceerd in: 1986
Onderwerpen:
Online toegang:http://dx.doi.org/10.1007/BF00515434
Formaat: Elektronisch Hoofdstuk
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=654439

MARC

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200 1 |a 10-Alkenylphenothiazines  |h 1  |i Synthesis and cis,trans-isomerization of 10-propenylphenothiazines  |f V. A. Anfinogenov [et al.] 
203 |a Text  |c electronic 
300 |a Title screen 
320 |a [References: 16 tit.] 
330 |a A study was carried out on the isomerization of 10-allylphenothiazine (I) in DMSO by the action of t-BuOK, KOH and NaOH. The isomerization proceeds stereospecifically at room temperature by the action of t-BuOK at an elevated temperature by the action of KOH and NaOH to give cis-10-propenylphenothiazine (II). The effect of the t-BuOK concentration, temperature and reaction time on the isomeric composition of the 10-propenylphenothiazines formed was studied. Under conditions of kinetic control, I gives II, which isomerizes under the reaction conditions to give an equilibrium mixture of cis- and trans-10-propenyl-phenothiazine with 44-45% trans isomer III. The isomerization temperature has virtually no effect on the II/III isomer ratio. 
333 |a Режим доступа: по договору с организацией-держателем ресурса 
461 |t Chemistry of Heterocyclic Compounds 
463 |t Vol. 22, iss. 1  |v [P. 100-103]  |d 1986 
610 1 |a электронный ресурс 
610 1 |a труды учёных ТПУ 
610 1 |a алкенилфенотиазины 
610 1 |a синтез 
610 1 |a исследование 
610 1 |a изомеризация 
610 1 |a температура 
701 1 |a Anfinogenov  |b V. A. 
701 1 |a Napilkova  |b O. A. 
701 1 |a Sirotkina  |b E. E. 
701 1 |a Filimonov  |b V. D.  |c Russian chemist  |c Professor of the TPU  |f 1945-  |g Viktor Dmitrievich  |3 (RuTPU)RU\TPU\pers\26423  |9 12127 
701 1 |a Ogorodnikov  |b V. D. 
801 2 |a RU  |b 63413507  |c 20170426  |g RCR 
856 4 |u http://dx.doi.org/10.1007/BF00515434 
942 |c CF