Synthesis and antiviral activity of antipyrine derivatives
| Parent link: | Pharmaceutical Chemistry Journal Vol. 26, iss. 6.— 1992.— [P. 426-430] |
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| Other Authors: | , , , , , , , , , |
| Summary: | Title screen In addition to antiinflammatory and analgesic activity, pyrazolones are known to possess antiviral activity [6-8]. Continuing this work, we have obtained some derivatives of antipyrine and 4- aminoantipyrine, and examined their antiviral spectrum of activity. In terms of their chemical structures, the compounds examined may be divided into the following groups: antipyrylamides of aliphatic aminoacids (I-XI), antipyryl- and isopropyl antipyrylamides of iodinated aromic carboxylic acids (XII-XX), 4-iodo- and 4-bromoantipyrine (XXI, XXII) and 4-formylantipyrine (XXIII), and derivatives of 4-formylantipyrine(XXIV, XXIX). ( 1 - Phenol-2,3-dimethyl-4-R- 5-pyrazolone). Режим доступа: по договору с организацией-держателем ресурса |
| Language: | English |
| Published: |
1992
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| Subjects: | |
| Online Access: | http://dx.doi.org/10.1007/BF00772907 |
| Format: | Electronic Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=654267 |
| Summary: | Title screen In addition to antiinflammatory and analgesic activity, pyrazolones are known to possess antiviral activity [6-8]. Continuing this work, we have obtained some derivatives of antipyrine and 4- aminoantipyrine, and examined their antiviral spectrum of activity. In terms of their chemical structures, the compounds examined may be divided into the following groups: antipyrylamides of aliphatic aminoacids (I-XI), antipyryl- and isopropyl antipyrylamides of iodinated aromic carboxylic acids (XII-XX), 4-iodo- and 4-bromoantipyrine (XXI, XXII) and 4-formylantipyrine (XXIII), and derivatives of 4-formylantipyrine(XXIV, XXIX). ( 1 - Phenol-2,3-dimethyl-4-R- 5-pyrazolone). Режим доступа: по договору с организацией-держателем ресурса |
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| DOI: | 10.1007/BF00772907 |