u-nanoparticles based sensors for voltammetric determination of glutathione

U-nanoparticles based sensors for voltammetric determination of glutathione

Bibliographic Details
Parent link:Current Analytical Chemistry
Vol. 12.— 2016
Corporate Author: Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Кафедра высшей математики и математической физики (ВММФ)
Other Authors: Perevezentseva D. O. Dariya Olegovna, Korshunov A. V. Andrey Vladimirovich, Gorchakov E. V. Eduard Vladimirovich, Bimatov V. I. Vladimir Ismagilovich, Fedorov V. E. Ivan Evgenjevich
Summary:Title screen
Abstract: Electrochemical behaviour of glutathione (GSH) at Au-nanoparticles based sensors (AuNP-sensors) was explored using cyclic voltammetry (CV). The obtained results reveal more catalytic activity of the AuNP-sensor toward the oxidation of GSH than gold film (Au-GE) modified graphite electrode due to increase in number of Au atoms at the surface of Au nanoparticles deposited at the graphite electrode. Electrocatalytic oxidation of GSH occurs at +0.05 V (vs. silver chloride ref. electrode) in 0.1 M NaOH and is revealed from CV as an “inverse” current peak in the cathodic direction of potential scan. Concentration of GSH in the interval 2–14 pM linearly influences on the peak height at AuNP-sensor with detectability threshold of 0.7 pM. The sequence of electrode reactions has been suggested which includes oxidation of Au nanoparticles when potentials scanned towards positive direction up to 0.8 V and consequent GSH electrocatalytic oxidation by Au(I)-oxide during the backward potential scan represented as the “inverse” peak. The proposed analytical method of GSH determination is simple, rapid and sensitive.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2016
Subjects:
электронный ресурс
труды учёных ТПУ
cyclic voltammetry
electrocatalysis
glutathione
циклическая вольтамперометрия
электрокатализ
глутатионы
Online Access:http://dx.doi.org/10.2174/1573411012666160606175735
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=653919

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