Voltammetry at a Hanging Mercury Drop Electrode as a Tool for the Study of the Interaction of Double-stranded DNA with Genotoxic 4-Nitrobiphenyl
| Parent link: | Electroanalysis Vol. 28, iss. 11.— 2016.— [P. 2760–2770] |
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| 1. autor: | |
| Korporacja: | |
| Kolejni autorzy: | , |
| Streszczenie: | Title screen Differential pulse voltammetry, cyclic voltammetry, alternating current voltammetry, and chronocoulometry at a hanging mercury drop electrode (HMDE) and DNA modified HMDE were used for the study of the interaction of 4-nitrobiphenyl (4-NBP) with double-stranded DNA and for the detection of DNA damage caused by its interaction with 4-NBP. Moreover, the interaction of DNA with intermediates of the 4-NBP reduction and with 4-aminobiphenyl, a metabolite of 4-NBP, was investigated. The mechanism of the electrochemical reduction of 4-NBP was investigated using CV, too. It was found that the reduction of 4-NBP is controlled by both diffusion and adsorption. The rate constant of the reduction and the diffusion coefficient were calculated as well. Режим доступа: по договору с организацией-держателем ресурса |
| Język: | angielski |
| Wydane: |
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | http://dx.doi.org/10.1002/elan.201600241 |
| Format: | Elektroniczne Rozdział |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=653305 |
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| 200 | 1 | |a Voltammetry at a Hanging Mercury Drop Electrode as a Tool for the Study of the Interaction of Double-stranded DNA with Genotoxic 4-Nitrobiphenyl |f E. Horakova, J. Barek, Vyskocil Vlastimil | |
| 203 | |a Text |c electronic | ||
| 300 | |a Title screen | ||
| 320 | |a [References: p. 2769-2770 (50 tit.)] | ||
| 330 | |a Differential pulse voltammetry, cyclic voltammetry, alternating current voltammetry, and chronocoulometry at a hanging mercury drop electrode (HMDE) and DNA modified HMDE were used for the study of the interaction of 4-nitrobiphenyl (4-NBP) with double-stranded DNA and for the detection of DNA damage caused by its interaction with 4-NBP. Moreover, the interaction of DNA with intermediates of the 4-NBP reduction and with 4-aminobiphenyl, a metabolite of 4-NBP, was investigated. The mechanism of the electrochemical reduction of 4-NBP was investigated using CV, too. It was found that the reduction of 4-NBP is controlled by both diffusion and adsorption. The rate constant of the reduction and the diffusion coefficient were calculated as well. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
| 461 | |t Electroanalysis | ||
| 463 | |t Vol. 28, iss. 11 |v [P. 2760–2770] |d 2016 | ||
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| 701 | 1 | |a Barek |b J. |c Czech chemist |c Professor of Tomsk Polytechnic University, candidate of chemical Sciences |f 1949- |g Jiri |3 (RuTPU)RU\TPU\pers\39743 | |
| 701 | 0 | |a Vyskocil Vlastimil | |
| 712 | 0 | 2 | |a Национальный исследовательский Томский политехнический университет (ТПУ) |b Институт природных ресурсов (ИПР) |b Кафедра гидрогеологии, инженерной геологии и гидрогеоэкологии (ГИГЭ) |3 (RuTPU)RU\TPU\col\18664 |
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