Radionuclide Assessment of Cardiac Function and Dyssynchrony in Children with Idiopathic Ventricular Tachycardia; Pacing and Clinical Electrophysiology (PACE); Vol. 39, iss. 11

Бібліографічні деталі
Parent link:Pacing and Clinical Electrophysiology (PACE)
Vol. 39, iss. 11.— 2016.— [P. 1213–1224]
Співавтор: Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Лаборатория № 31 ядерного реактора (Лаборатория № 31 ЯР)
Інші автори: Zavadovsky K. V. Konstantin Valerievich, Saushkin V. V. Viktor Vyacheslavovich, Khlynin M. S. Mikhail Sergeevich, Popov S. V. Sergey Valentinovich, Lishmanov Yu. B. Yury Borisovich
Резюме:Title screen
Background The aim of the study was to evaluate the impact of idiopathic ventricular tachycardia and premature ventricular beats on cardiac function and dyssynchrony and to elucidate relationships between data of scintigraphic and intracardiac electrophysiology studies (EPSs). Methods The study comprised 64 patients with idiopathic ventricular arrhythmias (VAs; median age of 14 years ranging from 8 to 18 years). The control group comprised 20 patients (median age of 12 ranging from 7 to 16 years) without cardiac arrhythmias. EPS and radiofrequency ablation (RFA) procedure for VA were performed in 21 children according to indications. The functional state of both ventricles was assessed by gated blood pool single photon emission computer tomography (GBP-SPECT) before and after RFA in all patients. Results Patients with VA had local areas of asynchronous myocardial contraction (AMC). Compared with the control group, VA patients had significantly higher values of end-diastolic volume, end-systolic volume, and lower contractility indices. Negative association was found between total numbers of AMC areas and cardiac contractility indices. Ectopic foci localization, determined based on EPS data, was associated with AMC areas topography based on GBP-SPECT. RFA procedure significantly improved cardiac contractility indices; AMC areas completely disappeared or decreased compared with the preoperative conditions. Conclusion In VA patients, AMC areas were localized mostly in the right ventricle. Comparison of the results of GBP-SPECT and EPS studies showed a relationship between AMC localizations and ectopic foci topography. The fact that AMC areas disappeared after RFA supports the hypothesis stating that the presence of AMC areas is a scintigraphic symptom of ectopic focus.
Режим доступа: по договору с организацией-держателем ресурса
Мова:Англійська
Опубліковано: 2016
Предмети:
Онлайн доступ:http://dx.doi.org/10.1111/pace.12948
Формат: Електронний ресурс Частина з книги
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=652563

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200 1 |a Radionuclide Assessment of Cardiac Function and Dyssynchrony in Children with Idiopathic Ventricular Tachycardia  |f K. V. Zavadovsky [et al.] 
203 |a Text  |c electronic 
300 |a Title screen 
330 |a Background The aim of the study was to evaluate the impact of idiopathic ventricular tachycardia and premature ventricular beats on cardiac function and dyssynchrony and to elucidate relationships between data of scintigraphic and intracardiac electrophysiology studies (EPSs). Methods The study comprised 64 patients with idiopathic ventricular arrhythmias (VAs; median age of 14 years ranging from 8 to 18 years). The control group comprised 20 patients (median age of 12 ranging from 7 to 16 years) without cardiac arrhythmias. EPS and radiofrequency ablation (RFA) procedure for VA were performed in 21 children according to indications. The functional state of both ventricles was assessed by gated blood pool single photon emission computer tomography (GBP-SPECT) before and after RFA in all patients. Results Patients with VA had local areas of asynchronous myocardial contraction (AMC). Compared with the control group, VA patients had significantly higher values of end-diastolic volume, end-systolic volume, and lower contractility indices. Negative association was found between total numbers of AMC areas and cardiac contractility indices. Ectopic foci localization, determined based on EPS data, was associated with AMC areas topography based on GBP-SPECT. RFA procedure significantly improved cardiac contractility indices; AMC areas completely disappeared or decreased compared with the preoperative conditions. Conclusion In VA patients, AMC areas were localized mostly in the right ventricle. Comparison of the results of GBP-SPECT and EPS studies showed a relationship between AMC localizations and ectopic foci topography. The fact that AMC areas disappeared after RFA supports the hypothesis stating that the presence of AMC areas is a scintigraphic symptom of ectopic focus. 
333 |a Режим доступа: по договору с организацией-держателем ресурса 
461 |t Pacing and Clinical Electrophysiology (PACE) 
463 |t Vol. 39, iss. 11  |v [P. 1213–1224]  |d 2016 
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701 1 |a Saushkin  |b V. V.  |g Viktor Vyacheslavovich 
701 1 |a Khlynin  |b M. S.  |g Mikhail Sergeevich 
701 1 |a Popov  |b S. V.  |g Sergey Valentinovich 
701 1 |a Lishmanov  |b Yu. B.  |c specialist in the field of medical technology  |c lead engineer aof Tomsk Polytechnic University, doctor of medical sciences  |f 1951-  |g Yury Borisovich  |3 (RuTPU)RU\TPU\pers\34200 
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