Concurrent thermochemoradiotherapy for brain high-grade glioma; AIP Conference Proceedings; Vol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016

Concurrent thermochemoradiotherapy for brain high-grade glioma; AIP Conference Proceedings; Vol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016

Bibliografske podrobnosti
Parent link:AIP Conference Proceedings
Vol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016.— 2016.— [020058, 6 p.]
Korporativna značnica: Национальный исследовательский Томский политехнический университет (ТПУ) Институт природных ресурсов (ИПР) Кафедра иностранных языков (ИЯПР)
Drugi avtorji: Ryabova A. I., Novikov V. A., Choinzonov Е. L., Gribova O. V., Startseva Zh. А., Bober E. E., Frolova I. G., Baranova A. V. Anastasia Viktorovna
Izvleček:Title screen
Despite the achievements in the current strategies for treatment, the prognosis in malignant glioma patients remains unsatisfactory. Hyperthermia is currently considered to be the most effective and universal modifier of radiotherapy and chemotherapy. Preliminary treatment outcomes for 28 patients with newly diagnosed (23) and recurrent (5) high-grade gliomas were presented. All the patients received multimodality treatment including surgery, thermoche-moradiotherapy followed by 4 cycles of adjuvant chemotherapy. All the patients endured thermochemoradiotherapy well. A complication, limited skin burn (II stage), was diagnosed in two cases and treated conservatively without treatment interruption. A month after thermochemoradiotherapy the results were as follows: complete regression was achieved in 4 cases, partial regression in 4 cases, stable disease in 14 cases and disease progression in 6 cases (one of them is pseudo-progression). After completing the adjuvant chemotherapy 2 more patients demonstrated complete response and 1 patient had disease progression. Introduction of local hyperthermia in multimodal therapy of malignant glioma does not impair the combined modality treatment tolerability of patients with malignant gliomas. A small number of studied patients and short follow-up time do not allow making reliable conclusions about the impact of local hyperthermia on the treatment outcomes; however, there is a tendency towards the increase in disease-free survival in the patients with newly diagnosed malignant gliomas.
Режим доступа: по договору с организацией-держателем ресурса
Jezik:angleščina
Izdano: 2016
Teme:
электронный ресурс
труды учёных ТПУ
мозг
злокачественные опухоли
злокачественные новообразования
глиомы
гипертония
Online dostop:http://dx.doi.org/10.1063/1.4960277
http://earchive.tpu.ru/handle/11683/35788
Format: Elektronski Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=652044

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