Hybrid calcium phosphate coatings for implants; AIP Conference Proceedings; Vol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016

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Parent link:AIP Conference Proceedings
Vol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016.— 2016.— [020047, 5 p.]
Korporace: Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Кафедра экспериментальной физики (ЭФ), Национальный исследовательский Томский политехнический университет (ТПУ) Институт физики высоких технологий (ИФВТ) Кафедра технологии силикатов и наноматериалов (ТСН)
Další autoři: Malchikhina A. I. Alena Igorevna, Shesterikov E. V. Evgeny Viktorovich, Bolbasov E. N. Evgeny Nikolaevich, Ignatov V. P. Viktor Pavlovich, Tverdokhlebov S. I. Sergei Ivanovich
Shrnutí:Title screen
Monophasic biomaterials cannot provide all the necessary functions of bones or other calcined tissues. It is necessary to create for cancer patients the multiphase materials with the structure and composition simulating the natural bone. Such materials are classified as hybrid, obtained by a combination of chemically different components. The paper presents the physical, chemical and biological studies of coatings produced by hybrid technologies (HT), which combine primer layer and calcium phosphate (CaP) coating. The first HT type combines the method of vacuum arc titanium primer layer deposition on a stainless steel substrate with the following micro-arc oxidation (MAO) in phosphoric acid solution with addition of calcium compounds to achieve high supersaturated state. MAO CaP coatings feature high porosity (2-8%, pore size 5-7 [mu]m) and surface morphology with the thickness greater than 5 [mu]m. The thickness of Ti primer layer is 5-40 [mu]m. Amorphous MAO CaP coating micro-hardness was measured at maximum normal load F[max]=300 mN. It was 3.1±0.8 GPa, surface layer elasticity modulus E=110±20 GPa, roughness R[a]=0.9±0.1 [mu]m, R[z]=7.5±0.2 [mu]m, which is less than the titanium primer layer roughness. Hybrid MAO CaP coating is biocompatible, able to form calcium phosphates from supersaturated body fluid (SBF) solution and also stimulates osteoinduction processes. The second HT type includes the oxide layer formation by thermal oxidation and then CaP target radio frequency magnetron sputtering (RFMS). Oxide-RFMS CaP coating is a thin dense coating with good adhesion to the substrate material, which can be used for metal implants. The RFMS CaP coating has thickness 1.6±0.1 [mu]m and consists of main target elements calcium and phosphorus and Ca/P ratio 2.4. The second HT type can form calcium phosphates from SBF solution. In vivo study shows that hybrid RFMS CaP coatingis biocompatible and produces fibrointegration processes.
Режим доступа: по договору с организацией-держателем ресурса
Jazyk:angličtina
Vydáno: 2016
Témata:
On-line přístup:http://dx.doi.org/10.1063/1.4960266
http://earchive.tpu.ru/handle/11683/35785
Médium: Elektronický zdroj Kapitola
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=652031

MARC

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330 |a Monophasic biomaterials cannot provide all the necessary functions of bones or other calcined tissues. It is necessary to create for cancer patients the multiphase materials with the structure and composition simulating the natural bone. Such materials are classified as hybrid, obtained by a combination of chemically different components. The paper presents the physical, chemical and biological studies of coatings produced by hybrid technologies (HT), which combine primer layer and calcium phosphate (CaP) coating. The first HT type combines the method of vacuum arc titanium primer layer deposition on a stainless steel substrate with the following micro-arc oxidation (MAO) in phosphoric acid solution with addition of calcium compounds to achieve high supersaturated state. MAO CaP coatings feature high porosity (2-8%, pore size 5-7 [mu]m) and surface morphology with the thickness greater than 5 [mu]m. The thickness of Ti primer layer is 5-40 [mu]m. Amorphous MAO CaP coating micro-hardness was measured at maximum normal load F[max]=300 mN. It was 3.1±0.8 GPa, surface layer elasticity modulus E=110±20 GPa, roughness R[a]=0.9±0.1 [mu]m, R[z]=7.5±0.2 [mu]m, which is less than the titanium primer layer roughness. Hybrid MAO CaP coating is biocompatible, able to form calcium phosphates from supersaturated body fluid (SBF) solution and also stimulates osteoinduction processes. The second HT type includes the oxide layer formation by thermal oxidation and then CaP target radio frequency magnetron sputtering (RFMS). Oxide-RFMS CaP coating is a thin dense coating with good adhesion to the substrate material, which can be used for metal implants. The RFMS CaP coating has thickness 1.6±0.1 [mu]m and consists of main target elements calcium and phosphorus and Ca/P ratio 2.4. The second HT type can form calcium phosphates from SBF solution. In vivo study shows that hybrid RFMS CaP coatingis biocompatible and produces fibrointegration processes. 
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