Radiopharmaceuticals for SPECT Cancer Detection; AIP Conference Proceedings; Vol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016

Bibliographic Details
Parent link:	AIP Conference Proceedings Vol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016.— 2016.— [020011, 7 p.]
Corporate Author:	Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Лаборатория № 31 ядерного реактора (Лаборатория № 31 ЯР)
Other Authors:	Chernov V. I. Vladimir Ivanovich, Medvedeva А. А. Anna Aleksndrovna, Zelchan R. V. Roman Vladimirovich, Sinilkin I. G. Ivan Gennadjevich, Stasyuk (Stasiuk) E. S. Elena Sergeyevna, Larionova L. A. Lyudmila Aleksandrovna, Slonimskaya E. M., Choynzonov E. L. Evgeny Lkhamatsyrenovich
Summary:	Title screen The purpose of the study was to assess the efficacy of single photon emission computed tomography (SPECT) with {199}Tl and {99}mTc-MIBI in the detection of breast, laryngeal and hypopharyngeal cancers. A total of 220 patients were included into the study: 120 patients with breast lesions (100 patients with breast cancer and 20 patients with benign breast tumors) and 100 patients with laryngeal/hypopharyngeal diseases (80 patients with laryngeal/hypopharyngeal cancer and 20 patients with benign laryngeal/hypopharyngeal lesions). No abnormal {199}Tl uptake was seen in all patients with benign breast and laryngeal lesions, indicating a 100% specificity of {199}Tl SPECT. In the breast cancer patients, the increased {199}Tl uptake in the breast was visualized in 94.8% patients, {99m}Tc-MIBI-in 93.4% patients. The increased {199}Tl uptake in axillary lymph nodes was detected in 60% patients, and {99m}Tc-MIBI-in 93.1% patients. In patients with laryngeal/hypopharyngeal cancer, the sensitivity of SPECT with {199}Tl and {99m}Tc-MIBI was 95%. The {199}Tl SPECT sensitivity in identification of regional lymph node metastases in the patients with laryngeal/hypopharyngeal cancer was 75% and the {99m}Tc-MIBI SPECT sensitivity was 17%. The data obtained showed that SPECT with {199}Tl and {99m}Tc-MIBI can be used as one of the additional imaging methods in detection of tumors. Режим доступа: по договору с организацией-держателем ресурса
Language:	English
Published:	2016
Subjects:	электронный ресурс труды учёных ТПУ радиофармпрепараты рак эмиссионная томография компьютерная томография визуализация опухоли ядерная медицина злокачественные опухоли
Online Access:	http://dx.doi.org/10.1063/1.4960230 http://earchive.tpu.ru/handle/11683/35771
Format:	Electronic Book Chapter
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=651982