Multifunctional polyelectrolyte microcapsules as a contrast agent for photoacoustic imaging in blood; Journal of Biophotonics; Vol. 9, iss. 8

Multifunctional polyelectrolyte microcapsules as a contrast agent for photoacoustic imaging in blood; Journal of Biophotonics; Vol. 9, iss. 8

Bibliographische Detailangaben
Parent link:Journal of Biophotonics.— , [s. a.]
Vol. 9, iss. 8.— 2016.— [P. 792-799]
Körperschaft: Национальный исследовательский Томский политехнический университет Управление проректора по научной работе и инновациям Центр RASA в Томске Лаборатория новых лекарственных форм
Weitere Verfasser: Yashchenok A. M. Alexey M., Jithin J. Jose, Trochet Ph. Philippe, Sukhorukov G. B. Gleb Borisovich, Gorin D. A. Dmitry Aleksandrovich
Zusammenfassung:Title screen
The polyelectrolyte microcapsules that can be accurate either visualized in biological media or in tissue would enhance their further in vivo application both as a carrier of active payloads and as a specific sensor. The immobilization of active species, for instance fluorescent dyes, quantum dots, metal nanoparticles, in polymeric shell enables visualization of capsules by optical imaging techniques in aqueous solution. However, for visualization of capsules in complex media an instrument with high contrast modality requires. Herein, we show for the first time photoacoustic imaging (PAI) of multifunctional microcapsules in water and in blood. The microcapsules exhibit greater photoacoustic intensity compare to microparticles with the same composition of polymeric shell presumably their higher thermal expansion. Photoacoustic intensity form microcapsules dispersed in blood displays an enhancement (2-fold) of signal compare to blood. Photoacoustic imaging of microcapsules might contribute to non-invasive carrier visualization and further their in vivo distribution.
Режим доступа: по договору с организацией-держателем ресурса
Sprache:Englisch
Veröffentlicht: 2016
Schlagworte:
электронный ресурс
труды учёных ТПУ
микрокапсулы
томография
Online-Zugang:http://dx.doi.org/10.1002/jbio.201500293
Format: Elektronisch Buchkapitel
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=650982

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