Comparative analysis of the effect of low-dimensional alumina structures on cell lines L929 and Neuro-2a

Comparative analysis of the effect of low-dimensional alumina structures on cell lines L929 and Neuro-2a

Bibliographic Details
Parent link:AIP Conference Proceedings
Vol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016.— 2016.— [020015, 6 p.]
Main Author: Fomenko A. N. Alla Nikolaevna
Corporate Author: Национальный исследовательский Томский политехнический университет (ТПУ) Институт физики высоких технологий (ИФВТ) Кафедра физики высоких технологий в машиностроении (ФВТМ) Сетевая научно-образовательная лаборатория "Медицинское материаловедение" (СНОЛ ММ)
Other Authors: Korovin M. S. Matvey Sergeevich
Summary:Title screen
The paper presents the toxicity evaluation of nanostructures on the basis of alumina of different shape (nanofibers, nanoplates, nanosheets, nanosheet agglomerates) and with similar physical and chemical properties (particle size, specific surface area, phase composition, and zeta potential). The nanostructures were examined by transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray diffraction (XRD), low-temperature nitrogen adsorption, and dynamic light scattering (DLS). The cytotoxicity of nanostructures was estimated using L929 fibroblast cells and Neuro-2a tumor cells. It has been found that the L929 cells are less subject to the influence of alumina nanoparticles than the Neuro-2a tumor cells. Probably, the differences in the proliferation activity of normal and tumor cells in contact with the synthesized nanostructures are due to a change in the pH of the cell microenvironment.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2016
Subjects:
электронный ресурс
труды учёных ТПУ
Online Access:http://dx.doi.org/10.1063/1.4960234
http://earchive.tpu.ru/handle/11683/35798
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=650283

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