Antitumor activity of low-dimensional alumina structures; AIP Conference Proceedings; Vol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016

Bibliografski detalji
Parent link:AIP Conference Proceedings
Vol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016.— 2016.— [020034, 9 p.]
Glavni autor: Korovin M. S. Matvey Sergeevich
Autor kompanije: Национальный исследовательский Томский политехнический университет (ТПУ) Институт физики высоких технологий (ИФВТ) Кафедра физики высоких технологий в машиностроении (ФВТМ) Сетевая научно-образовательная лаборатория "Медицинское материаловедение" (СНОЛ ММ)
Daljnji autori: Fomenko A. N. Alla Nikolaevna
Sažetak:Title screen
Nano-dimensional materials have recently attracted much attention with respect to their potential role in medicine. Physical mechanisms of interaction of nanoparticles with tumor cells will help to develop new methods for cancer disease treatment. Based on aluminum oxide phases, positively charged low-dimensional structures have different shape: agglomerates of nanosheets, nameplates, cone-shaped nanoaggregates were synthesized with the help of aluminum nanoparticles. The cytotoxicity effect of these low-dimensional structures on A549, HeLa, MDA, PyMT tumor cells was studied. It was shown that agglomerates of nanosheets were more toxic for investigating cell lines. Agglomerates of nanosheets had a medium toxic effect at a concentration of 10?mg/ml while nameplates and cone-shaped nanoaggregates were nontoxic. The toxic effect of agglomerates of nanosheets correlates with their shape, mainly the presence of multiple edges.
Режим доступа: по договору с организацией-держателем ресурса
Jezik:engleski
Izdano: 2016
Teme:
Online pristup:http://dx.doi.org/10.1063/1.4960253
http://earchive.tpu.ru/handle/11683/35781
Format: Elektronički Poglavlje knjige
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=650281

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