Antitumor activity of low-dimensional alumina structures; AIP Conference Proceedings; Vol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016
| Parent link: | AIP Conference Proceedings Vol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016.— 2016.— [020034, 9 p.] |
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| Riassunto: | Title screen Nano-dimensional materials have recently attracted much attention with respect to their potential role in medicine. Physical mechanisms of interaction of nanoparticles with tumor cells will help to develop new methods for cancer disease treatment. Based on aluminum oxide phases, positively charged low-dimensional structures have different shape: agglomerates of nanosheets, nameplates, cone-shaped nanoaggregates were synthesized with the help of aluminum nanoparticles. The cytotoxicity effect of these low-dimensional structures on A549, HeLa, MDA, PyMT tumor cells was studied. It was shown that agglomerates of nanosheets were more toxic for investigating cell lines. Agglomerates of nanosheets had a medium toxic effect at a concentration of 10?mg/ml while nameplates and cone-shaped nanoaggregates were nontoxic. The toxic effect of agglomerates of nanosheets correlates with their shape, mainly the presence of multiple edges. Режим доступа: по договору с организацией-держателем ресурса |
| Lingua: | inglese |
| Pubblicazione: |
2016
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| Accesso online: | http://dx.doi.org/10.1063/1.4960253 http://earchive.tpu.ru/handle/11683/35781 |
| Natura: | Elettronico Capitolo di libro |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=650281 |
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| 200 | 1 | |a Antitumor activity of low-dimensional alumina structures |f M. S. Korovin, A. N. Fomenko | |
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| 330 | |a Nano-dimensional materials have recently attracted much attention with respect to their potential role in medicine. Physical mechanisms of interaction of nanoparticles with tumor cells will help to develop new methods for cancer disease treatment. Based on aluminum oxide phases, positively charged low-dimensional structures have different shape: agglomerates of nanosheets, nameplates, cone-shaped nanoaggregates were synthesized with the help of aluminum nanoparticles. The cytotoxicity effect of these low-dimensional structures on A549, HeLa, MDA, PyMT tumor cells was studied. It was shown that agglomerates of nanosheets were more toxic for investigating cell lines. Agglomerates of nanosheets had a medium toxic effect at a concentration of 10?mg/ml while nameplates and cone-shaped nanoaggregates were nontoxic. The toxic effect of agglomerates of nanosheets correlates with their shape, mainly the presence of multiple edges. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
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| 463 | 0 | |0 (RuTPU)RU\TPU\network\17033 |t Vol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016 |o Proceedings of the International conference, 22-25 March 2016, Tomsk, Russia |f National Research Tomsk Polytechnic University (TPU) ; eds. E. Y. Gutmanas ; O. B. Naimark ; Yu. P. Sharkeev |v [020034, 9 p.] |d 2016 | |
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