Effects of Water-Soluble Polysaccharides with Different Chemical Structure, Isolated from Acorus calamus L. and Trifolium pratense L., on Nitric Oxide Production: A Screening Study; Bulletin of Experimental Biology and Medicine; Vol. 160, iss. 3

Effects of Water-Soluble Polysaccharides with Different Chemical Structure, Isolated from Acorus calamus L. and Trifolium pratense L., on Nitric Oxide Production: A Screening Study

Λεπτομέρειες βιβλιογραφικής εγγραφής
Parent link:Bulletin of Experimental Biology and Medicine: Scientific Journal
Vol. 160, iss. 3.— 2016.— [P. 330–335]
Συγγραφή απο Οργανισμό/Αρχή: Национальный исследовательский Томский политехнический университет Институт неразрушающего контроля Кафедра экологии и безопасности жизнедеятельности
Άλλοι συγγραφείς: Ligachyova A. A., Danilets M. G., Trofimova E. S. Evgeniya Sergeevna, Sherstoboev E. Yu. Evgeny Yurjevich, Zhdanov V. V. Vladimir Vladimirovich, Gurjev A. M. Artyom Mikhaylovich, Belousov M. V. Mikhail Valerievich, Yusubov M. S. Mekhman Suleiman-Ogly (Suleimanovich), Korzh A. P. Anna Petrovna, Krivoshchekov S. V. Sergey Vladimirovich, Dygay A. M. Aleksandr Mikhaylovich
Περίληψη:Title screen
Screening study of the effects of sweet flag (Acorus calamus L.) rhizome and clover (Trifolium pratense L.) aerial part on the production of NO by mouse macrophages was carried out. The polysaccharides were separated by ion exchange chromatography into fractions differing by monomeric composition and ramification type and were used in concentrations of 20, 40, and 100 μg/ml. Four fractions of Acorus calamus L. (PSF-101, PSF-102, PSF-103, and PSF-105), used in different concentrations, moderately stimulated nitrite production by macrophages. Three of five Trifolium pratense L. polysaccharides (PS62-3, PS62-4, and PS62-5) exhibited a significant specific effect on NO production. Rhamnogalactouronans from clover PS63-3 in all concentrations and from PS62-5 in a concentration of 100 μg/ml exhibited the highest activity, comparable to the NO-stimulatory activity of the reference LPS, while polysaccharide PS62-3 in a concentration of 40 μg/ml exhibited even higher activity.
Режим доступа: по договору с организацией-держателем ресурса
Γλώσσα:Αγγλικά
Έκδοση: 2016
Θέματα:
электронный ресурс
труды учёных ТПУ
Διαθέσιμο Online:http://dx.doi.org/10.1007/s10517-016-3163-2
Μορφή: Ηλεκτρονική πηγή Κεφάλαιο βιβλίου
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=650099
Περιγραφή
Περίληψη:Title screen
Screening study of the effects of sweet flag (Acorus calamus L.) rhizome and clover (Trifolium pratense L.) aerial part on the production of NO by mouse macrophages was carried out. The polysaccharides were separated by ion exchange chromatography into fractions differing by monomeric composition and ramification type and were used in concentrations of 20, 40, and 100 μg/ml. Four fractions of Acorus calamus L. (PSF-101, PSF-102, PSF-103, and PSF-105), used in different concentrations, moderately stimulated nitrite production by macrophages. Three of five Trifolium pratense L. polysaccharides (PS62-3, PS62-4, and PS62-5) exhibited a significant specific effect on NO production. Rhamnogalactouronans from clover PS63-3 in all concentrations and from PS62-5 in a concentration of 100 μg/ml exhibited the highest activity, comparable to the NO-stimulatory activity of the reference LPS, while polysaccharide PS62-3 in a concentration of 40 μg/ml exhibited even higher activity.
Режим доступа: по договору с организацией-держателем ресурса
DOI:10.1007/s10517-016-3163-2

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