Serum Glutathione in Patients with Schizophrenia in Dynamics of Antipsychotic Therapy

Chi tiết về thư mục
Parent link:Bulletin of Experimental Biology and Medicine: Scientific Journal
Vol. 160, iss. 2.— 2016.— [P. 283–285]
Tác giả của công ty: Национальный исследовательский Томский политехнический университет Институт неразрушающего контроля Кафедра экологии и безопасности жизнедеятельности
Tác giả khác: Ivanova S. A. Svetlana Aleksandrovna, Smirnova L. P., Shchigoreva Y. G. Yuliya Gennadjevna, Semke A. V. Arkady Valentinovich, Bokhan N. A. Nikolay Aleksandrovich
Tóm tắt:Title screen
Serum concentrations of oxidized and reduced glutathione were measured in 73 patients with schizophrenia at admission and in dynamics of therapy with traditional and atypical antipsychotic drugs. The level of reduced glutathione in patients with schizophrenia with manifest clinical symptoms was lower than in normal subjects. Atypical neuroleptics produced virtually no effects on the glutathione system, while therapy with typical antipsychotics led to further decrease in the levels of reduced glutathione, thus aggravating the imbalance of metabolic processes typical of schizophrenia.
Режим доступа: по договору с организацией-держателем ресурса
Ngôn ngữ:Tiếng Anh
Được phát hành: 2016
Những chủ đề:
Truy cập trực tuyến:http://dx.doi.org/10.1007/s10517-015-3151-y
Định dạng: Điện tử Chương của sách
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=649823
Miêu tả
Tóm tắt:Title screen
Serum concentrations of oxidized and reduced glutathione were measured in 73 patients with schizophrenia at admission and in dynamics of therapy with traditional and atypical antipsychotic drugs. The level of reduced glutathione in patients with schizophrenia with manifest clinical symptoms was lower than in normal subjects. Atypical neuroleptics produced virtually no effects on the glutathione system, while therapy with typical antipsychotics led to further decrease in the levels of reduced glutathione, thus aggravating the imbalance of metabolic processes typical of schizophrenia.
Режим доступа: по договору с организацией-держателем ресурса
DOI:10.1007/s10517-015-3151-y