Serum Glutathione in Patients with Schizophrenia in Dynamics of Antipsychotic Therapy; Bulletin of Experimental Biology and Medicine; Vol. 160, iss. 2

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Parent link:Bulletin of Experimental Biology and Medicine: Scientific Journal
Vol. 160, iss. 2.— 2016.— [P. 283–285]
Korporativní autor: Национальный исследовательский Томский политехнический университет Институт неразрушающего контроля Кафедра экологии и безопасности жизнедеятельности
Další autoři: Ivanova S. A. Svetlana Aleksandrovna, Smirnova L. P., Shchigoreva Y. G. Yuliya Gennadjevna, Semke A. V. Arkady Valentinovich, Bokhan N. A. Nikolay Aleksandrovich
Shrnutí:Title screen
Serum concentrations of oxidized and reduced glutathione were measured in 73 patients with schizophrenia at admission and in dynamics of therapy with traditional and atypical antipsychotic drugs. The level of reduced glutathione in patients with schizophrenia with manifest clinical symptoms was lower than in normal subjects. Atypical neuroleptics produced virtually no effects on the glutathione system, while therapy with typical antipsychotics led to further decrease in the levels of reduced glutathione, thus aggravating the imbalance of metabolic processes typical of schizophrenia.
Режим доступа: по договору с организацией-держателем ресурса
Jazyk:angličtina
Vydáno: 2016
Témata:
On-line přístup:http://dx.doi.org/10.1007/s10517-015-3151-y
Médium: Elektronický zdroj Kapitola
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=649823
Popis
Shrnutí:Title screen
Serum concentrations of oxidized and reduced glutathione were measured in 73 patients with schizophrenia at admission and in dynamics of therapy with traditional and atypical antipsychotic drugs. The level of reduced glutathione in patients with schizophrenia with manifest clinical symptoms was lower than in normal subjects. Atypical neuroleptics produced virtually no effects on the glutathione system, while therapy with typical antipsychotics led to further decrease in the levels of reduced glutathione, thus aggravating the imbalance of metabolic processes typical of schizophrenia.
Режим доступа: по договору с организацией-держателем ресурса
DOI:10.1007/s10517-015-3151-y