Serum Glutathione in Patients with Schizophrenia in Dynamics of Antipsychotic Therapy

Bibliographic Details
Parent link:Bulletin of Experimental Biology and Medicine: Scientific Journal
Vol. 160, iss. 2.— 2016.— [P. 283–285]
Corporate Author: Национальный исследовательский Томский политехнический университет Институт неразрушающего контроля Кафедра экологии и безопасности жизнедеятельности
Other Authors: Ivanova S. A. Svetlana Aleksandrovna, Smirnova L. P., Shchigoreva Y. G. Yuliya Gennadjevna, Semke A. V. Arkady Valentinovich, Bokhan N. A. Nikolay Aleksandrovich
Summary:Title screen
Serum concentrations of oxidized and reduced glutathione were measured in 73 patients with schizophrenia at admission and in dynamics of therapy with traditional and atypical antipsychotic drugs. The level of reduced glutathione in patients with schizophrenia with manifest clinical symptoms was lower than in normal subjects. Atypical neuroleptics produced virtually no effects on the glutathione system, while therapy with typical antipsychotics led to further decrease in the levels of reduced glutathione, thus aggravating the imbalance of metabolic processes typical of schizophrenia.
Режим доступа: по договору с организацией-держателем ресурса
Published: 2016
Subjects:
Online Access:http://dx.doi.org/10.1007/s10517-015-3151-y
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=649823
Description
Summary:Title screen
Serum concentrations of oxidized and reduced glutathione were measured in 73 patients with schizophrenia at admission and in dynamics of therapy with traditional and atypical antipsychotic drugs. The level of reduced glutathione in patients with schizophrenia with manifest clinical symptoms was lower than in normal subjects. Atypical neuroleptics produced virtually no effects on the glutathione system, while therapy with typical antipsychotics led to further decrease in the levels of reduced glutathione, thus aggravating the imbalance of metabolic processes typical of schizophrenia.
Режим доступа: по договору с организацией-держателем ресурса
DOI:10.1007/s10517-015-3151-y