CYP1A2 and CYP2D6 Gene Polymorphisms in Schizophrenic Patients with Neuroleptic Drug-Induced Side Effects; Bulletin of Experimental Biology and Medicine; Vol. 160, iss. 5
| Parent link: | Bulletin of Experimental Biology and Medicine: Scientific Journal Vol. 160, iss. 5.— 2016.— [P. 718-721] |
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| Erakunde egilea: | |
| Beste egile batzuk: | , , , , , , , , , |
| Gaia: | Title screen Polymorphic variants of CYP1A2 and CYP2D6 genes of the cytochrome P450 system were studied in patients with schizophrenia with drug-induced motor disorders and hyperprolactinemia against the background of long-term neuroleptic therapy. We revealed an association of polymorphic variant C-163A CYP1A2*1F of CYP1A2 gene with tardive dyskinesia and association of polymorphic variant 1846G>A CY2D6*4 and genotype A/A of CYP2D6 gene (responsible for debrisoquin-4-hydroxylase synthesis) with limbotruncal tardive dyskinesia in patients with schizophrenia receiving neuroleptics for a long time. Режим доступа: по договору с организацией-держателем ресурса |
| Hizkuntza: | ingelesa |
| Argitaratua: |
2016
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| Gaiak: | |
| Sarrera elektronikoa: | http://dx.doi.org/10.1007/s10517-016-3250-4 |
| Formatua: | Baliabide elektronikoa Liburu kapitulua |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=649456 |