The Importance of X-ray Crystal Structure Determinations for Pharmacy; Chemicke Listy; Vol. 110, iss. 1
| Parent link: | Chemicke Listy Vol. 110, iss. 1.— 2016.— [P. 40-47] |
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| Autor corporatiu: | |
| Altres autors: | , , , |
| Sumari: | Title screen X-ray structure analysis results have been widely used in the pharmaceutical research, development and control, especially for mapping polymorphism, to determine the chirality of active substances, in the pharmaceutical documentation and patent policy for many years. The greatest progress in X-ray diffraction techniques has been made in improving the quality of the poor material for successful data collection (magnetically oriented microcrystal arrays, serial snapshot crystallography). Prospects of the pharmaceutical application of X-ray crystallography lie in the acceleration of data collection, time-resolved structural studies obtained from the material of pharmaceutical batches without modification, and, in addition to that, in solving structures of semi-solid and amorphous phases and monitoring structural changes in drug formulations. |
| Idioma: | txec |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | http://www.chemicke-listy.cz/common/article-vol_110-issue_1-page_40.html |
| Format: | MixedMaterials Electrònic Capítol de llibre |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=648827 |
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| 200 | 1 | |a The Importance of X-ray Crystal Structure Determinations for Pharmacy |d Vyznam stanoveni rtg krystalovych struktur pro farmacii |f B. Kratokhvil, E. I. Korotkova, M. P. Husak, A. M. Jegorov | |
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| 330 | |a X-ray structure analysis results have been widely used in the pharmaceutical research, development and control, especially for mapping polymorphism, to determine the chirality of active substances, in the pharmaceutical documentation and patent policy for many years. The greatest progress in X-ray diffraction techniques has been made in improving the quality of the poor material for successful data collection (magnetically oriented microcrystal arrays, serial snapshot crystallography). Prospects of the pharmaceutical application of X-ray crystallography lie in the acceleration of data collection, time-resolved structural studies obtained from the material of pharmaceutical batches without modification, and, in addition to that, in solving structures of semi-solid and amorphous phases and monitoring structural changes in drug formulations. | ||
| 461 | |t Chemicke Listy | ||
| 463 | |t Vol. 110, iss. 1 |v [P. 40-47] |d 2016 | ||
| 510 | 1 | |a Vyznam stanoveni rtg krystalovych struktur pro farmacii |z cze | |
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| 701 | 1 | |a Husak |b M. P. |g Michal P. | |
| 701 | 1 | |a Jegorov |b A. M. |g Alexandr M. | |
| 712 | 0 | 2 | |a Национальный исследовательский Томский политехнический университет |b Институт природных ресурсов |b Кафедра физической и аналитической химии |3 (RuTPU)RU\TPU\col\18656 |9 27109 |
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