New preparation method of PLA-based biomaterials containing molecular iodine layer on their surface; Recent advances on Mathematical Models for Engineering Science
| Parent link: | Recent advances on Mathematical Models for Engineering Science.— 2015.— [P. 25-30] |
|---|---|
| Corporate Authors: | Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Кафедра экспериментальной физики (ЭФ), Национальный исследовательский Томский политехнический университет (ТПУ) Институт физики высоких технологий (ИФВТ) Кафедра биотехнологии и органической химии (БИОХ) |
| Andre forfattere: | Goreninsky (Goreninskii) S. I. Semen Igorevich, Stankevich K. S. Ksenia Sergeevna, Efimova E. V. Elena Vyacheslavovna, Danilenko N. V. Nadezhda Viktorovna, Tverdokhlebov S. I. Sergei Ivanovich, Filimonov V. D. Viktor Dmitrievich |
| Summary: | Title screen Poly(lactic) acid (PLA) is biodegradable polymer that nowadays is being used as a material for various medical applications. However, it has several drawbacks like low biological activity and absence of radiopacity. Iodine and iodine-containing compounds are well-known for their antibacterial and radiopaque properties. In order to improve PLA-based biomaterials properties we developed new surface modification method based on “solvent/non-solvent” treatment with subsequent entrapment of iodine either from its vapour or solutions. It was shown that developed technique allows us to create an iodine layer on PLA-based materials surface with estimated amount of iodine from 10-9 to 10-8 g/cm2 . Stability of such layer was also investigated and it was shown that it is stable enough to be used for medical applications requiring long-term iodine release into water medium. |
| Sprog: | engelsk |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | http://www.wseas.us/e-library/conferences/2015/Michigan/MABI/MABI-04.pdf |
| Format: | Electronisk Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=648602 |
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