New preparation method of PLA-based biomaterials containing molecular iodine layer on their surface; Recent advances on Mathematical Models for Engineering Science

Bibliographic Details
Parent link:Recent advances on Mathematical Models for Engineering Science.— 2015.— [P. 25-30]
Corporate Authors: Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Кафедра экспериментальной физики (ЭФ), Национальный исследовательский Томский политехнический университет (ТПУ) Институт физики высоких технологий (ИФВТ) Кафедра биотехнологии и органической химии (БИОХ)
Other Authors: Goreninsky (Goreninskii) S. I. Semen Igorevich, Stankevich K. S. Ksenia Sergeevna, Efimova E. V. Elena Vyacheslavovna, Danilenko N. V. Nadezhda Viktorovna, Tverdokhlebov S. I. Sergei Ivanovich, Filimonov V. D. Viktor Dmitrievich
Summary:Title screen
Poly(lactic) acid (PLA) is biodegradable polymer that nowadays is being used as a material for various medical applications. However, it has several drawbacks like low biological activity and absence of radiopacity. Iodine and iodine-containing compounds are well-known for their antibacterial and radiopaque properties. In order to improve PLA-based biomaterials properties we developed new surface modification method based on “solvent/non-solvent” treatment with subsequent entrapment of iodine either from its vapour or solutions. It was shown that developed technique allows us to create an iodine layer on PLA-based materials surface with estimated amount of iodine from 10-9 to 10-8 g/cm2 . Stability of such layer was also investigated and it was shown that it is stable enough to be used for medical applications requiring long-term iodine release into water medium.
Language:English
Published: 2015
Subjects:
Online Access:http://www.wseas.us/e-library/conferences/2015/Michigan/MABI/MABI-04.pdf
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=648602

MARC

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200 1 |a New preparation method of PLA-based biomaterials containing molecular iodine layer on their surface  |f S. I. Goreninsky [et al.] 
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330 |a Poly(lactic) acid (PLA) is biodegradable polymer that nowadays is being used as a material for various medical applications. However, it has several drawbacks like low biological activity and absence of radiopacity. Iodine and iodine-containing compounds are well-known for their antibacterial and radiopaque properties. In order to improve PLA-based biomaterials properties we developed new surface modification method based on “solvent/non-solvent” treatment with subsequent entrapment of iodine either from its vapour or solutions. It was shown that developed technique allows us to create an iodine layer on PLA-based materials surface with estimated amount of iodine from 10-9 to 10-8 g/cm2 . Stability of such layer was also investigated and it was shown that it is stable enough to be used for medical applications requiring long-term iodine release into water medium. 
463 |t Recent advances on Mathematical Models for Engineering Science  |o proceedings 12th International Conference on Mathematical Biology Ecology (MABE '15) and 6th International Conference on Mathematical Models for Engineering Science (MMES '15), East Lansing, September 20-22, 2015 г.  |f Michigan State University ; ed. I. J. Rudas  |v [P. 25-30]  |d 2015 
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