New preparation method of PLA-based biomaterials containing molecular iodine layer on their surface
| Parent link: | Recent advances on Mathematical Models for Engineering Science.— 2015.— [P. 25-30] |
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| Enti autori: | , |
| Altri autori: | , , , , , |
| Riassunto: | Title screen Poly(lactic) acid (PLA) is biodegradable polymer that nowadays is being used as a material for various medical applications. However, it has several drawbacks like low biological activity and absence of radiopacity. Iodine and iodine-containing compounds are well-known for their antibacterial and radiopaque properties. In order to improve PLA-based biomaterials properties we developed new surface modification method based on “solvent/non-solvent” treatment with subsequent entrapment of iodine either from its vapour or solutions. It was shown that developed technique allows us to create an iodine layer on PLA-based materials surface with estimated amount of iodine from 10-9 to 10-8 g/cm2 . Stability of such layer was also investigated and it was shown that it is stable enough to be used for medical applications requiring long-term iodine release into water medium. |
| Lingua: | inglese |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | http://www.wseas.us/e-library/conferences/2015/Michigan/MABI/MABI-04.pdf |
| Natura: | Elettronico Capitolo di libro |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=648602 |
| Riassunto: | Title screen Poly(lactic) acid (PLA) is biodegradable polymer that nowadays is being used as a material for various medical applications. However, it has several drawbacks like low biological activity and absence of radiopacity. Iodine and iodine-containing compounds are well-known for their antibacterial and radiopaque properties. In order to improve PLA-based biomaterials properties we developed new surface modification method based on “solvent/non-solvent” treatment with subsequent entrapment of iodine either from its vapour or solutions. It was shown that developed technique allows us to create an iodine layer on PLA-based materials surface with estimated amount of iodine from 10-9 to 10-8 g/cm2 . Stability of such layer was also investigated and it was shown that it is stable enough to be used for medical applications requiring long-term iodine release into water medium. |
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