Opioids as Triggers of the Adaptive Phenomenon of Ischemic Preconditioning of the Heart

書目詳細資料
Parent link:Neuroscience and Behavioral Physiology.— , 1967-
Vol. 46, iss. 3.— 2016.— [P. 319-327]
企業作者: Национальный исследовательский Томский политехнический университет Институт природных ресурсов Кафедра экономики природных ресурсов
其他作者: Maslov L. N. Leonid Nikolaevich, Naryzhnaya N. V. Nataliya Vladimirovna, Podoksenov Yu. K. Yury Kirilovich, Mrochek A. G. Aleksandr Gennadievich, Gorbunov A. S. Aleksandr Sergeevich, Tsibulnikov S. Yu. Sergey Yurjevich
總結:Title screen
Transient ischemia/reperfusion has been shown to evoke increases in enkephalin levels in myocardial tissue. Blockade of δ opioid receptors eliminates the cardioprotective effect of ischemic preconditioning both in vivo and in vitro. Inhibition of κ1 opioid receptors eliminates the cardioprotective effect of preconditioning only in vitro. Agonists of μ, δ1, δ2, and κ1 opioid receptors imitate the cardioprotective effect of preconditioning. These results indicate that endogenous opioid peptides are triggers of ischemic preconditioning.
Режим доступа: по договору с организацией-держателем ресурса
出版: 2016
主題:
在線閱讀:http://dx.doi.org/10.1007/s11055-016-0236-7
格式: 電子 Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=647811